GAMBARAN INTERAKSI OBAT PENYAKIT JANTUNG KORONER DENGAN SINDROM METABOLIK PADA PASIEN RAWAT JALAN DI RS TK II DR. SOEPRAOEN MALANG

  • Rakhmadani Gadis Aprilianti Institut Teknologi, Sains, dan Kesehatan RS dr Soepraoen Malang
  • Beta Herilla Sekti Institut Teknologi, Sains, dan Kesehatan RS dr Soepraoen Malang
  • Lilik Nur Hidayati Institut Teknologi, Sains, dan Kesehatan RS dr Soepraoen Malang
Keywords: Drug Interaction, Coronary Heart Disease

Abstract

Drug interaction is the effect of a drug that is caused when there are two or more drugs that interact and affect the body's response to treatment. The method used in this study is a descriptive study using a cross-sectional observational method with retrospective observations in October - December 2020. Patient data collection was obtained from patient medical records using a purposive sampling technique with inclusion criteria. A total of 89 patients were taken as samples. Data analysis using MEDSCAPE and drugs.com applications. A total of 82 prescriptions have the potential for drug interactions, where the most significant level of drug interaction is moderate level (81.48%, these include aspirin with candesartan and bisoprolol with amlodipine. The most drug interaction is the interaction between aspirin and bisoprolol which is classified as a minor interaction (17.74%). The most frequently used type of drug is bisoprolol (22.18%) and the most frequently used drug class is beta blocker

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Published
2022-01-28
How to Cite
Aprilianti, R., Sekti, B., & Hidayati, L. (2022). GAMBARAN INTERAKSI OBAT PENYAKIT JANTUNG KORONER DENGAN SINDROM METABOLIK PADA PASIEN RAWAT JALAN DI RS TK II DR. SOEPRAOEN MALANG. Jurnal Riset Kefarmasian Indonesia, 4(1), 59-73. https://doi.org/10.33759/jrki.v4i1.222
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