FORMULASI DAN UJI DAYA HAMBAT SABUN CAIR EKSTRAK ETANOL SERAI WANGI (Cymbopogon nardus L) TERHADAP PERTUMBUHAN Staplylococcus aureus

  • Rinaldi Rinaldi Akademi Analis Farmasi dan Makanan Banda Aceh
  • Fauziah Fauziah Akademi Analis Farmasi dan Makanan Banda Aceh
  • Rizka Mastura Akademi Analis Farmasi dan Makanan Banda Aceh
Keywords: sabun cair, Formulasi, daya hambat, Staphylococus aureus

Abstract

Citronella (Cymbopogon Nardus.L) contains essential oil compounds, saponins, polyphenols and flavonoids which are antibacterial. The use of active compounds of Citronella is formulated into antibacterial liquid soap preparations. This study aims to determine the characteristics of liquid soap and its inhibition against the growth of Staphylococcus aureus. This research is experimental to formulate liquid soap containing ethanol extract of lemongrass sticks at concentrations of 9% (F1), 18% (F2) and 24% (F3). The test parameters for liquid soap preparations include organoleptic test (shape, aroma, color), homogeneity test, pH test, foam height test, foam stability test, free alkaline test and inhibition test against the growth of Staphylococcus aureus using the Kirby-Bauer method. The results showed that the liquid soap preparations in the F1, F2 and F3 formulas were liquid, had a distinctive aroma of Citronella and were brown in color, homogeneous. The pH values, foam height, foam stability and free alkaline content of liquid soap were F1 (12; 70 mm; 85.7% and 0.14%), F2 (11. 80 mm, 87.5% and respectively). 0.10%), F3 (10.100 mm, 90% and 0.08%). The formula inhibition zone diameters are 32.06 mm, 25.6 mm and 29.2 mm, respectively. The conclution is the characteristics of the liquid soap with the ethanol extract of Citronella (Cymbopogon Nardus.L) meet the requirements as liquid soap. The greatest inhibitory effectiveness on the growth of Staphylococcus aureus was a formula at a concentration of 24% (F3) with a strong category. 

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References

Aziz. Analisis in vitro aktivitas antibakteri daun sisik naga (Drymoglossum pilosellaoides) terhadap bakteri Vibrio harveyi dan Vibrio parahaemolyticus. Fakultas Perikanan dan Ilmu Kelautan, Universitas Borneo Tarakan. 2019. Journal of Aquaculture and Fish Health Vol. 8 No.2.

Badan Standarisasi Nasional. Standar Nasional Indonesia. Sabun Mandi Cair. Jakarta. 1996. Pp 1-10.

Basuki D. Aktifitas Antibakteri Ekstrak Etil Asetat Tanaman Serai (Cymbopogon nardus (L.) Rendle) Terhadap Escherichia coli Dan Staphylococcus aureus Multiresisten Serta Bioautografinya. Skripsi Jurusan Farmasi Fakultas Farmasi Universitas Muhammadiyah Surakarta. 2011.

Mumpuni A.S dan Sasongko Heru.‘Mutu Sabun Transparan Ekstrak Etanol Herba Pegagan (Centella asiatica L.) setelah Penambahan Sukrosa. Universitas sebelas maret, surakarta. Vol.7, No.1. 2017, Hal. 71-78 ISSN: 2088 4559.

Pratama N dan Andi Ilham. Pengaruh Kadar Minyak Zaitun dalam Krim Ekstrak Daun Camelia Sinensis L Terhadap Karakteristik Fisik dan Aktivitas Antibakteri S.aureus. Skripsi Program Studi Farmasi Fakultas Ilmu Kesehatan Universitas Muhammadiyah Malang. 2017.

Sukawaty Y, Husul W, Ananda VA. Formulasi sediaan sabun mandi padat ekstrak etanol umbi bawang tiwai (Eleutherine bulbosa (mill.) Urb.). Akademi Farmasi Samarinda. Media Farmasi vol. 13 no. 1. 2016 : 14-22

Surjowardojo P, Tri E.S, Gabriel R.Sirait. Daya hambat dekok kulit apel manalagi (Malus sylvestrs Mill.) terhadap pertumbuhan Staphylococcus aureusdan Pseudomonas sp. penyebab mastitis pada sapi perah. Fakultas Peternakan, Universitas Brawijaya, Malang. 2015. J. Ternak Tropika Vol. 16, No.2: 40-48.

Tong, S.Y.T., Davis, J.S., Eichenberger, E., Holland, T.L., Fowler, F.G. Staphylococcus aureus infections: Epidemiology, pathophysiology, clinical manifestations, and management. Clinical Microbiology Reviews, 2015. 28(3), 603-66.

Wasitaatmadja, S.M. Penuntun Ilmu Kosmetik Medik. Penerbit Universitas Indonesia. Jakarta. 1997.

Widyasanti A, Adryani TW dan Rosalinda S. Pembuatan Sabun Mandi Cair Berbahan baku Minyak Kelapa Dengan Berbagai Variasi Konsentrasi Ekstrak Teh Putih. Departemen Teknik Pertanian Universitas Padjadjaran, Bandung. 2019. Agrointek Vol.13 No.2. DOI: http://dx.doi.org/10.21107/agrointek.v13i2.5102.
Published
2021-01-16
How to Cite
Rinaldi, R., Fauziah, F., & Mastura, R. (2021). FORMULASI DAN UJI DAYA HAMBAT SABUN CAIR EKSTRAK ETANOL SERAI WANGI (Cymbopogon nardus L) TERHADAP PERTUMBUHAN Staplylococcus aureus. Jurnal Riset Kefarmasian Indonesia, 3(1), 45-57. https://doi.org/10.33759/jrki.v3i1.115
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