2026-10-07T20:57:36Z http://jurnalfarmasi.or.id/index.php/jrki/oai

oai:ojs.pkp.sfu.ca:article/6 2019-05-23T09:11:53Z jrki:ART driver

EVALUASI SIFAT FISIK SEDIAAN SHAMPO EKSTRAK DAUN KATUK (Sauropus androgynus (L) Merr) DENGAN BERBAGAI VARIASI VISCOSITY AGENT Rashati, Dewi Eryani, Mikhania Christiningtyas HPMC, sodium CMC, Carbopol, Sauropus androgynus (L) Merr Sauropus androgynus (L) Merr leaf in Indonesia called katuk have strong antioxidant activity with IC50 80,01 ppm. The aims of this research is want to know physical properties of katuk leaf shampo which is formulated in various formulas. In this research katuk was formulated in shampoo with viscocity agent (HPMC, sodium CMC and Carbopol) in various concentration. The result showed that all shampoo formulas had low jasmine smell, but had different in form and colour. Shampoo viscocity increased with increased viscocity agent. The highest viscocity showed by F7 with 0,5% carbopol concentration. pH test showed that the shampoo with HPMC and sodium CMC had pH value 6. pH value of shampoo with carbopol was 5. All of pH formulas meet the requirement of SNI standard. Statistical result showed that the physical properties of foam high, viscocity and pH all formulas had significant difference.   APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-01-19 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/6 10.33759/jrki.v1i1.6 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 1 (2019): Jurnal Riset Kefarmasian Indonesia; 56-63 2655-8289 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/6/16 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/7 2019-05-23T09:11:53Z jrki:ART driver

Pemanfaatan Ekstrak Daun Teh (Camellia sinensis L) Dari Perkebunan Kemuning Kab. Karang Anyar dalam Pembuatan Sabun Padat Transparan dan Uji Aktivitas Antibakteri pada Staphyloccocus aureus Setiawan, Iwan Saryati, Dwi Astian, Astian Ekstrak daun teh Sabun padat transparan Staphyloccocus aureus Kemuning’s plantations in Karang Anyar Regency are famous for their lush tea plantations and good quality. Tea leaves contain several substances including flavonoids, 30- 40% polyphenols, caffeine, essential oils and tannins. The famous tea leaf polyphenols are catechins. Catechins have properties as antidiarrheal, antibacterial, especially against Staphyloccocus aureus bacteria, which is one of the gram-positive bacteria that cause infections in the skin. Based on this, tea leaf extract can be used as a natural supplement in the manufacture of transparent soap products. In this study tea leaf extract became one of the components in making transparent soap by adding tea leaf extract to formula 1 (0%), formula 2 (1.5%), formula 3 (3%) and formula 4 (4, 5%). Then transparent soap preparations were tested for organoleptic and quality quality including moisture and vaporizing soap content, amount of fatty acids, free alkali content and levels of unbunned fractions and anti-bacterial activity against the growth of Staphyloccocus aureus bacteria. Based on the results of the study, it was found that transparent 4 solid soap with 4.5% tea leaf extract content had the darkest color of solid soap, evaporated water and substance content, free alkali content, fatty acid, acidity level (pH), unbonded fraction level and the highest foam stability. Formula 4 solid soap also has the best inhibitory power against the growth of Staphyloccocus aureus bacteria. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-01-11 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/7 10.33759/jrki.v1i1.7 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 1 (2019): Jurnal Riset Kefarmasian Indonesia; 21-29 2655-8289 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/7/7 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/8 2019-05-23T09:11:53Z jrki:ART driver

PENGARUH EDUKASI FARMASIS TERHADAP MOTIVASI DAN KEPATUHAN PENGGUNA PROGRAM TERAPI RUMATAN METADON DI PUSKESMAS TAMBORA PADA BULAN FEBRUARI - APRIL 2015 Halim, Marta Kumala, Shirly Hersunaryati, Yetti pharmacist education methadone maintenance motivation and compliance This study was triggered by the large number of users of Methadone Maintenance Therapy Program (MMTP) who Dropped Out due to lack of motivation and compliance. The purpose of this study was to increase the motivation and compliance of the Tambora Community Health Center MMTP users. The study design used the quasi-experimental method with the pretest-the posttest the group was not comparable. Voluntary research samples amounted to 100 with a distribution of @ 50 for the control group (KK) and @ 50 for the treatment group (KE). Based on the results of data analysis, the following results were obtained: (1) There was an increase in the motivation and compliance variables for the group given education with lectures and leaflets. (3) Pharmacist education (variable knowledge, attitudes and actions) simultaneously can increased the motivation of users with a score of 15.4% (p value 0.00 <0.05) in MMTP at the Tambora Community Health Center. (3) Pharmacist education (variable knowledge, attitudes and actions) simultaneously increases the compliance of service users in MMTP Tambora Community Health Center with a score of 12.7% (p value 0.00 <0.05). The Conclusion pharmacist education can increase motivation and compliance to users of Tambora Community Health Center MMTP services. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-01-20 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/8 10.33759/jrki.v1i1.8 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 1 (2019): Jurnal Riset Kefarmasian Indonesia; 82-92 2655-8289 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/8/19 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/10 2019-05-23T09:11:53Z jrki:ART driver

POLA PENGGUNAAN OBAT ANTIRETROVIRAL (ARV) PADA RESEP PASIEN RAWAT JALAN DARI KLINIK HIV/AIDS SALAH SATU RUMAH SAKIT SWASTA DI KOTA BANDUNG Anggriani, Ani Lisni, Ida Liku, Olga Susana Antiretroviral, HIV/AIDS, Pattern of Drug Use ABSTRACT The Human Immunodeficiency Virus (HIV) continues to be a major global public health issue, which targets the human immune system. The using of ARVs in the treatment of HIV / AIDS increased life expectancy for PLHIV (People With HIV / AIDS). This study aims to determine the description of the using of ARV drugs in outpatients of the HIV / AIDS Clinic and assessed their suitability with established treatment standards. This research was carried out in a descriptive non-experimental manner, with data collection carried out retrospectively, used patient prescription data from April to December 2017. The results of quantitative studies showed 87% were male patients, and the largest age group was 20-29 years (39%) . Class of antiretroviral drugs used were Nucleoside / Nucleotide Reverse Transcriptase Inhibitors (NRTIs), Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs), and Protease Inhibitors (PI), with a combination of antiretroviral drugs most was the combination of first-line tenofovir + lamivudine + efavirenz (69%) while the second-line drug zidovudine + lamivudine + lopinavir / ritonavir  was 1%. The most commonly used comorbid drug was cotrimoxazole. For qualitative data, the accuracy of combination and dose of ARV drugs was 100% in accordance with Permenkes No. 87/ 2014, with 79% of patients adhered to antiretroviral treatment every month. The potential for most ARV drug interactions with other drugs for the moderate category was zidovudin + cotrimoxazole (11%) which occured pharmacokinetically by decreasing renal clearance of zidovudine and glucuronide metabolites. In conclusion, the pattern of used of ARV drugs had met the standard of Permenkes No.87/2014, with the most used were the first line combination of tenofovir + lamivudine + efavirenz. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-01-19 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/10 10.33759/jrki.v1i1.10 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 1 (2019): Jurnal Riset Kefarmasian Indonesia; 64-81 2655-8289 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/10/17 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/12 2019-05-23T09:11:53Z jrki:ART driver

KAJIAN PENGOBATAN TRADISIONAL CACAR MENURUT TERJEMAHAN LONTAR USADA KACACAR Sutrisna, I Nyoman Gede Tri Widyastuti, Ni Luh Gede Cahyadi, Kadek Duwi Usada Kacacar Cacar Pengobatan Cacar The Traditional medicine in Bali is a concept of Balinese culture that is used for generations. Usada is a knowledge of traditional Balinese medicine as a source of concepts to solve problems in the health sector. Healing (usada) is found in lontar called lontar usada. Lontar Usada Kacacar is one of the usada which discusses smallpox. The purpose of this study is to find out information contained in Lontar Usada Kacacar. Information includes the type of smallpox, treatment ingredients, dosage form and method of use. In addition, in research can be inform a plants that are used as traditional smallpox drugs. Healing in Bali is based on lontar, the research this time was carried out on eaves of Usada Kacacar. This research was conducted descriptively to the translation of Lontar Usada Kacacar translated by I Gusti Ngurah Wiriawan, S.S. The results of the translation of Lontar Usada Kacacar made in table form include the types of smallpox, medicinal herbs, how to use and use spells. The results of the table found information on 100 medicinal herbs, 75 types of smallpox, 107 types of plants, 10 types of methods of use and 16 methods of treatment accompanied by spells. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-01-15 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/12 10.33759/jrki.v1i1.12 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 1 (2019): Jurnal Riset Kefarmasian Indonesia; 41-55 2655-8289 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/12/11 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/15 2019-05-23T09:11:53Z jrki:ART driver

PERBANDINGAN METODE EKSTRAKSI EKSTRAK UMBI BAWANG RAMBUT (Allium chinense G.Don.) MENGGUNAKAN PELARUT ETANOL 70% TERHADAP RENDEMEN DAN SKRINING FITOKIMIA Supomo, Supomo Warnida, Husnul Said, Bagus Moch Digesti, Maserasi, Allium chinense, Skrining Fitokimia, Rendemen Allium chinense are plants that contain bioactive compounds such as alkaloids, flavonoids, and saponins. The rendement of an extract may be affected by the extraction mentod used. This study aims to determine the effect of maseration and digestion extraction method on rendemen and identification of secondary metabolite in the extract of the hair onion bulbs. Research conducted is an experimental study.  The samples used were hair bulbs obtained in Kota Bangun, East Kalimantan, extracted wiyh 2 extraction methods of maceration and digestion using ethanol 70% solvent and done as much as 3 times replication. Identification of secondary metabolite compounds was performed by phytochemical screening including test of alkaloids, flavonoids, saponins, tannins, and steroids. From the test data is processed by statistical analysis. The result of rendement with 3 times replikation of digesti mentod obtained by 20,02 gram, 19,03 gram, and 19,17 gram. While the maseration method obtained for 12,38 grams, 12,45 grams, and 15,91 grams. So there are differences between the results of the results of digestion mentod and maseration mentod. Based on phytochemical screening tets showed that the thick extract of hair onion bulbs contain compounds alkaloids, flavonoids, and saponins. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-01-11 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/15 10.33759/jrki.v1i1.15 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 1 (2019): Jurnal Riset Kefarmasian Indonesia; 30-40 2655-8289 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/15/8 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/18 2019-05-27T15:52:26Z jrki:ART driver

PERBEDAAN KUALITAS TANAMAN MINT (Mentha spicata L) HIDROPONIK DAN KONVENSIONAL BERDASARKAN MORFOLOGI TANAMAN, PROFIL KROMATOGRAM, DAN KADAR MINYAK ATSIRI Pratiwi, Pramita Yuli Mardiyaningsih, Ana Widarti, Emi Mentha spicata L essential oil hydroponic Mint is one of the essential oil-producing plants. Essential oils of Mentha spicata L or spearmint are widely used as raw materials in the food, beverage and pharmaceutical preparations industries. The main components of spearmint are karvon, limonen, cineol, dihydrocarvol, myrcene, and 0.5% menthol. The components contained in spearmint have properties as herbal remedies. Plant cultivation greatly determined the results of standardized drug ingredients. Cultivation with the right planting system can affect the quality of simplicia. This research were a descriptive study to differentiate the quality of plants. This study aimed to determine differences in plant morphology, chromatogram profile and levels of spearmint essential oil between hydroponic and conventional planting systems. Observation of plant morphology includes the size, color of the stem and leaves. Essential oil content is calculated from refined oil by steam and water distillation method. Spearmint oil was analyzed on thin layer chromatography methode using the silica gel F254 as a stationary phase and hexane-ethyl acetate (8: 2) as a mobile phase, with spot visualization under UV254 and anisaldehyde-H2SO4 . The results showed that the morphology of Mentha spicata L with hydrophonic  planting systems had a bigger size in stem and leaves, but the leaves had more bright green than a conventional plant. The chromatogram profile did not show differences in the number of spots and Rf. Mentha spicata L with conventional planting systems had a sharper intensity of color on one of the volatile oil spot, and suggested  due to menthol. The levels volatile oil of Mentha spicata L hydroponic and conventional were determined as 0.0326% and 0.0323% . The Independent T-test analysis  showed that there were not a significant differences. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-05-24 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/18 10.33759/jrki.v1i2.18 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 2 (2019): Jurnal Riset Kefarmasian Indonesia; 148-156 2655-8289 10.33759/jrki.v1i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/18/35 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs2.jurnalfarmasi.or.id:article/19 2018-11-02T03:13:10Z jurnal-apdfi:ART driver

oai:ojs.pkp.sfu.ca:article/20 2019-05-27T15:52:26Z jrki:ART driver

Formulasi Dan Uji Aktivitas Anti Bakteri Masker Gel Peel-Off Ekstrak Daun Pacar Air (Impatiens balsamina linn.) Dengan Kombinasi Basis PVA dan HPMC Saputra, Sony Andika Lailiyah, Munifatul Erivina, Adella Formulasi Gell pell off Impatiens balsamina Linn Peel-off gel mask is one of the practical masks, because after dry the mask can be directly removed without rinsing. In this research, a peel-off gel mask formulation from a pacar air leaf extract (Impatiens balsamina Linn.) Has antibacterial activity against Staphylococus Aureus bacteria. The peel-off gel mask is prepared in 3 formulas by varying the PVA and HPMC concentrations of F1 (1: 2,6), F2 (1: 3), F3 (1: 3,5). Evaluation of gel quality used is organoleptic test, viscosity, adhesion, drying time, dispersion, pH. Testing of antibacterial activity was done by using the diffusion method of wells. The positive control used was clindamycin phosphate 1.2%, the negative control used was the base of the peel-off gel mask. Results of physical evaluation and antibacterial activity test were analyzed using SPSS software with trust level of 0.05. Based on the results obtained F3 is the optimum formula, because F3 has a corresponding pH of 5.2 ± 0.10, the corresponding depth of 6.85 ± 0.13, the fastest drying time of 21.68 ± 0.33 and the anti-activity the best bacteria. Based on testing of antibacterial activity of F1, F2 and F3 have antibacterial activity against Staphylococus Aureus bacteria. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-05-19 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/20 10.33759/jrki.v1i2.20 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 2 (2019): Jurnal Riset Kefarmasian Indonesia; 114-122 2655-8289 10.33759/jrki.v1i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/20/25 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/21 2019-05-27T15:52:26Z jrki:ART driver

PENINGKATAN DISOLUSI ROSUVASTATIN CALSIUM DARI SEDIAAN TABLET DENGAN TEKNIK LIQUISOLID DAN PEMBENTUKAN KOMPLEKS INKLUSI Sutiswa, Shandra Isasi Cahyati, Yeyet Mudhakir, Diky Rosuvastatin calcium, Liquisolid, Inclusion Complex, Dissolution Rate Rosuvastatin calcium is a salt form of rosuvastatin with antilipidemia activity. Rosuvastatin Calcium classified in class two of Biopharmaceutics Clasification System (BCS)  has low solubility in water (17.96 mg / L) and high permeability. Based on this, rosuvastatin calcium needs to be formulated appropriately in order to produce high bioavailability and maximum therapeutic effect. The bioavailability of BCS 2 drug is determined by the dissolution rate of the drug in gastrointestinal fluid so that a technique is needed in formulating the drug. This study aims to develop a formulation technique for rosuvastatin calcium tablets through liquisolid technique and formation of inclusion complexes with β-cyclodextrin in order to increase the rate of dissolution. Tablet formulation with liquisolid technique was made with a concentration of 10% rosuvastatin calcium in propylene glycol, with a ratio of US2® (carrier) and Aerosil 200 (coating) made with a ratio of 10: 1 and 20: 1. In addition to the formulation with liquisolid technique, formulations were also carried out with the complex inclusion technique of rosuvastatin calcium-β-cyclodextrin using kneading method and freeze drying method with a mol ratio of 1: 1 and 1: 2. The liquisolid system and inclusion complexes formed were characterized using FTIR and SEM. Characterization results indicated changes in the form of polymorphous rosuvastatin calcium. Tablet formulations were made by direct compression using a liquisolid system and an inclusion complex equivalent to 10 mg of rosuvastatin calcium. Based on the results of the ANOVA statistical test and further LSD tests showed that calcium rosuvastatin tablets made with liquisolid and inclusion complexes can increase the dissolution rate compared to pure rosuvastatin calcium tablets and inovator rosuvastatin calcium tablets. The highest dissolution rate was produced by liquisolid R20: 1 tablet at 60 minutes at 85.53 ± 1.02% in an enzyme-free simulated gastric fluid dissolution medium and 110.02 ± 1.71% in an enzyme-free simulated intestinal fluid dissolution medium. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-05-18 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/21 10.33759/jrki.v1i2.21 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 2 (2019): Jurnal Riset Kefarmasian Indonesia; 93-102 2655-8289 10.33759/jrki.v1i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/21/31 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/22 2019-05-27T15:52:26Z jrki:ART driver

DAYA ANTIBAKTERI SEDIAAN GEL EKSTRAK ETANOL DAUN MURBEI (Morus alba L.) SEBAGAI OBAT LUKA PADA KULIT TERHADAP Staphylococcus aureus Asri, Muhammad Bahar, Fahril Sediaan Gel, Daun Murbei (Morus alba L.), Antibakteri, Staphylococcus aureus, Konsentrasi Hambat Minimum A research concerning the antibacterial effect of mulberry leaves (Morusalba L.) ethanol extract gel as cure of skin wounds against Staphylococcus aureus bacteria.This research is aimed to know the antibacterial effect of mulberry leaves (Morusalba L.) ethanol extract gel as cure of skin wounds against Staphylococcus aureus bacteria and determine inhibitor concentration minimum value. It was an experimental research which conducted in the laboratory to test the antibacterial effect of mulberry leaves (Morusalba L.) ethanol extract gel as cure of skin wounds against Staphylococcus aureus bacteria.            The result of observation showed that 1% concentration produced diameter of resistance zone average as 0.83 mm, 3% concentration were 0.97 mm and 5% concentration were 1.13 mm. It can be concluded that; 1) mulberry leaves ethanol extract gel stock on 1%, 3%, and 5% concentration have a weak resistance based on Antimicrobial resistor category ;2) inhibitor concentration minimum value of 1% concentration, was the lowest concentration that still giving antibacterial effect to against of Staphylococcus aureus bacterial APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-05-19 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/22 10.33759/jrki.v1i2.22 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 2 (2019): Jurnal Riset Kefarmasian Indonesia; 123-130 2655-8289 10.33759/jrki.v1i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/22/26 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/23 2019-05-27T15:52:26Z jrki:ART driver

PENETAPAN KADAR FENOLIK TOTAL FRAKSI POLR DAN NONPOLAR DAUN RAMBAI LAUT (Sonneratia caseolaris L.) DENGAN METODE SPEKTROFOTOMETRI UV-Vis Jubaidah, Siti Sundu, Reksi Sabriningsih, Nur rambai laut, phenolic, U-Vis spectrophotometry Rambai laut (Soneratia caseolaris L.) is a type of tree that grows in riverbank swamps or mangrove forests which contains one of the secondary metabolites in the form of phenolic compounds. The purpose of this study was to determine the total phenolic content of polar and nonpolar fractions of sea rambai leaves using UV-Vis spectrophotometry method. Research conducted is non-experimental. The stages of the study included the determination of plants, sampling, making samples, making extracts, determining the water content of extracts, fractionation using polar and nonpolar fractions, phytochemical screening test of ethanol extract and fractionation results and determination of total phenolic levels by UV-Vis spectrophotometry. The results showed that rambai laut leaf in polar fraction had a total phenolic content of 213.49 ± 1.2227 mg GAE / g, which means that in each gram the polar fraction is equivalent to 213.49 mg of gallic acid, whereas in the nonpolar fraction of rambai laut leaves is obtained 55.79 ± 1.0809 mg GAE / g which means that in each gram the nonpolar fraction is equivalent to 55.79 mg of gallic acid. Total phenolic content is greater in the polar fraction. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-05-22 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/23 10.33759/jrki.v1i2.23 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 2 (2019): Jurnal Riset Kefarmasian Indonesia; 140-147 2655-8289 10.33759/jrki.v1i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/23/34 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/24 2019-05-27T15:52:26Z jrki:ART driver

UJI EFEK ANALGETIK EKSTRAK ETANOL DAUN NANGKA (Artocarpus heterophyllus Lam.) TERHADAP MENCIT (Mus musculus) YANG DIINDUKSI ASAM ASETAT Auliah, Nielma Lotuconsina, Ari Aprianto Thalib, Muthmainnah Kata Kunci : Analgetik, daun nangka (Artocarpus heterophyllus Lam.) Asam Asetat.           Research has been carried out with the title "Test of the Analgetic Effect of Ethanol Extract of Jackfruit Leaves (Artocarpus heterophyllus Lam.) On Acetic Acid-induced Mice (mus musculus). Analgesics or painkillers are drugs that reduce or eliminate taste without losing consciousness. One of the traditional plants commonly used empirically is jackfruit leaves (Artocarpus heterophyllus Lam.). This study aims to determine the analgetic effect of ethanol extract of jackfruit leaves (Artocarpus heterophylus Lam.) At a dose of 100 mg / kgBB, 300 mg / kgBB and 600 mg / kgBW on acetic acid induced male mice (Mus musculus). This research is an experimental study and uses the chemical induction method. The results obtained in the form of% protection inhibition stretching ethanol extract of jackfruit leaves (Artocarpus heterophyllus Lam.) At a dose of 100mg / kgBB (28.79%); 300mg / kgBB (53.31%); 600mg / kgBB (60.70%). From the results of the research that has been done it can be concluded that the ethanol extract of jackfruit leaves (Artocarpus heterophyllus Lam.) Has the highest analgesic effect at a dose of 600mg / kgBW having a percentage of protection of 66.70%. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-05-18 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/24 10.33759/jrki.v1i2.24 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 2 (2019): Jurnal Riset Kefarmasian Indonesia; 103-113 2655-8289 10.33759/jrki.v1i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/24/24 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs2.jurnalfarmasi.or.id:article/25 2018-11-02T06:01:21Z jurnal-apdfi:ART

oai:ojs2.jurnalfarmasi.or.id:article/27 2018-11-02T07:14:11Z jurnal-apdfi:ART driver

oai:ojs2.jurnalfarmasi.or.id:article/28 2018-11-03T12:38:14Z jurnal-apdfi:ART driver

oai:ojs2.jurnalfarmasi.or.id:article/30 2018-12-05T11:12:43Z jrki:ART driver

oai:ojs.pkp.sfu.ca:article/31 2019-09-20T04:37:20Z jrki:ART driver

PERBANDINGAN UJI DAYA HAMBAT ANTARA EKSTRAK AKAR BELUNTAS DENGAN KULIT BUAH MAHKOTA DEWA TERHADAP PERTUMBUHAN BAKTERI E.COLI Agustina, Ika Efrilia, Mega Lisnawati, Nia Beluntas (Pluchea indica Less) crown god (Phaleria macrocarpa (Scheff.) Boerl.) Escherichia coli Antibacterial When this has been much studied extracts of herbs or traditional medicines, among other crops beluntas (Pluchea indica Less) and mahkota dewa (Phaleria macrocarpa (Scheff.) Boerl.) As an antibacterial. Previous research has suggested that the rind of the gods crown and root beluntas known to have antibacterial activity, but please be more certain with the same methods and evaluation in testing the antibacterial activity of both plants against bacteria Escherichia coli. Are both these plants have a vigorous activity the same or different from one another. The method used to test the antibacterial activity is using the disc. The results showed beluntas root extract has inhibitory activity against Escherichia coli was higher than fruit skin extracts gods crown with a minimum concentration of 6%, while the fruit skin extracts crowns a new god looks at a concentration of 12%. Based on the paired t-test showed that there is a significant difference between the antibacterial activity of root extracts beluntas with fruit leather crown god. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-09-12 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/31 10.33759/jrki.v1i3.31 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 3 (2019): Jurnal Riset Kefarmasian Indonesia; 238-247 2655-8289 10.33759/jrki.v1i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/31/43 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/33 2020-01-29T13:04:59Z jrki:ART driver

FORMULASI MASKER GEL PEEL-OFF PERASAN LIDAH BUAYA (Aloe vera L.) DENGAN GELLING AGENT POLIVINIL ALKOHOL Santoso, Ivan Prayoga, Tria Agustina, Ika Rahayu, Wiwit Setya peeled off gel mask aloe vera juice polyvinyl alcohol Aloe vera (Aloe Vera L.) is a plant which commonly used by local people as moisturizer. The usage of aloe vera can be applied in form of peeled off gel mask with polyvinyl alcohol as gelling agent. The goal of this research is to determine the influence of increase of polyvinyl alcohol as gelling agent to the formulation of peeled off mask from aloe vera juice. The formulation was made in a few concentration, 10%, 12%, and 14% by adding 0,5% of aloe vera juice. After that, the formulation evaluated for 4 weeks about the organoleptics, homogenity, pH, drying time and viscosity. The date of pH test and drying time analyzed by using one way ANOVA statistically and then followed by Tukey HSD test and the viscosity analyzed by using Kruskall Wallis statistically which result in the significantcy less than 0,05 that mean there are difference in drying time and viscosity, on the other hand there is no difference in pH. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2020-01-15 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/33 10.33759/jrki.v2i1.33 Jurnal Riset Kefarmasian Indonesia; Vol. 2 No. 1 (2020): Jurnal Riset Kefarmasian Indonesia; 17-25 2655-8289 10.33759/jrki.v2i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/33/56 Copyright (c) 2020 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/35 2019-05-27T15:52:26Z jrki:ART driver

PENENTUAN NILAI SPF EKSTRAK ETIL ASETAT DAUN MANGGA GEDONG MENGGUNAKAN SPEKTROFOTOMETRI UV - VIS Lisnawati, Nia N.U, M Fathan Nurlitasari, Dwi SPF Gedong Mango Leaf Extract UV-Vis Spectrophotometry One way that is done to reduce the negative impact of sunlight is by using sunscreen. Sunscreen can protect the skin by spreading sunlight or absorbing sunlight radiation energy that is about the skin. Phenolic compounds especially flavonoid groups have the potential as a sunscreen because of the chromophore group (single conjugated double bond) capable of absorbing UV light both UV A and UV B, thus reducing the intensity of the skin. Flavonoids have three properties of photoprotektor that is UV absorption, antioxidant properties, and modulate some DNA signaling pathways. The potential of sunscreen can be expressed with Sun Protection Factor (SPF). SPF is designated as UV protection B and is not specifically intended to resist UV A and UV C. The purpose of this research is to know the value of SPF (Sun Protection Factor) of ethyl acetate extract of mango gedong leaves using UV-Vis spectrophotometry. Simplicia gedong mango leaves were extracted using ethyl acetate solvent by reflux. Gedong mango leaf extract identified flavonoid compound using 10% NaOH and H2SO4 (concentrated). Determination of SPF (Sun Protection Factor) value of med gedong leaf extract using UV-Vis spectrophotometry method. The concentration of ethyl acetate extract of mango gedong leaves used was 120 ppm, 240 ppm and 360 ppm. The SPF (Sun Protection Factor) values were analyzed using Mansur method. The result of identification of flavonoid compound showed that the extract of ethyl acetate of mango gedong leaves positively contain flavonoids, while the result of SPF (Sun Protection Factor) extract of ethyl acetate of mango gedong leaves was 5,556; 16,675 and 22,243. The SPF (Sun Protection Factor) extract of 5,556 muddy ethyl acetate leaves including moderate protection type, 16,675 and 22,243 including ultra-protection type when tested using UV-Vis spectrophotometry by Mansur method APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-05-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/35 10.33759/jrki.v1i2.35 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 2 (2019): Jurnal Riset Kefarmasian Indonesia; 157-165 2655-8289 10.33759/jrki.v1i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/35/36 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/36 2019-05-27T15:52:26Z jrki:ART driver

FORMULASI SEDIAAN GEL EKSTRAK ETANOL 96% RIMPANG JAHE MERAH (Zingiber officinale Rosc. Var. Rubrum) DENGAN HIDROKSIETIL SELULOSA SEBAGAI GELLING AGENT L, Pricillya M Falestin, Senny Listy Kartika Julisna, Siska Formulation Red Ginger’s Root’s Extract of Ethanol 96% Hydroxiethyl cellulose Zingiber officinale Rosc. Var. Rubrum is a plant that has been determined to have antibacteria activity for Propionibacterium acnes which serve as one of the cause of acnes. Gel is the topical form used to acne’s medication. Hydroxiethyl Cellulose is used as gelling agent in gel of red ginger’s root’s ethanol 96% extract. The goal of the research is to determine the influence of increased concentration of hydroxiethyl cellulose to the  formulation of  red ginger’s root’s extract of ethanol 96%. The gel was made into 3 formulas with each concentration of 2%, 2.5%, and 3%. Each formulas wastested about the organoleptics, homogenity, pH, and viscosity. The result shows that on organoleptic test, the gels don’t have any change, they are homogen and their pH were stable. Based on the viscosity test, 1st, 2nd and 3rd formulas have some increase with the addition of storage’s time. The formula 1 have less viscocity with the concentration of about 2%. Based on this research, we can conclude that the 1 st formula was the best one based on the physical, chemical quality and the organoleptic test. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-05-19 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/36 10.33759/jrki.v1i2.36 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 2 (2019): Jurnal Riset Kefarmasian Indonesia; 13`1-139 2655-8289 10.33759/jrki.v1i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/36/33 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/43 2019-05-23T09:11:53Z jrki:ART driver

UJI Brine Shrimp Lethality Test (BSLT) UMBI BAWANG TIWAI (Eleutherine bulbosa (Mill.) Urb) DAN UJI TOKSISITAS AKUT FRAKSI AKTIF Lestari, Dwi Kartika, Rudi Marliana, Eva Eleutherine bulbosa BSLT chloroform fraction acute toxicity test Eleutherine bulbosa (Mill.) Urb come from the Iridaceae family, this species contains secondary metabolites in the form of flavonoids and quinones. This research method includes Brine Shrimp Lethality Test (BSLT) toxicity using Artemia salina Leach larvae to determine the LC50 value. This study used experimental methods pharmacologically using a completely randomized design in the same direction pattern in the selection of test animals, 25 animals used were white mice divided into 5 groups with 5 mice per group, with 4 hours observed to find out toxic symptoms and continued observation every 24 hours to see death. Testing of BSLT results showed that ethanol extract had LC50 toxicity = 66.68 ppm (very toxic category), n-hexane fraction had LC50 toxicity = 47.64 ppm (very toxic category), chloroform fraction had LC50 toxicity = 295.1 ppm ( toxic category), and the water fraction has a toxicity of LC50 = 194.54 ppm (very toxic category). The chloroform fraction is an active fraction. Acute toxicity test LD50 value according to the calculation method of Miller Tainter Probit (187,499 mg/KgBB), the method of calculation of Thompson Weil (182,810 mg/KgBB), how to calculate Indonesian Pharmacopoeia (187,068 mg/KgBB). Based on the three calculations, the LD50 value is in the medium category (50-500 mg/kgBB). APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-01-11 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/43 10.33759/jrki.v1i1.43 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 1 (2019): Jurnal Riset Kefarmasian Indonesia; 1-10 2655-8289 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/43/5 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/44 2019-09-19T18:39:27Z jrki:ART driver

OPTIMASI ASAM STEARAT DAN TEA PADA FORMULA SEDIAAN KRIM EKSTRAK KULIT PISANG KEPOK (Musa paradisiaca L.) Saryanti, Dwi Setiawan, Iwan Safitri, Romadona Ayu Optimization, Cream, Banana Kepok Peel, Simplex Lattice Design Banana kepok peel has flavonoid compounds used as antioxidants. The aim of this research is to get optimum formula of cream by combination of stearic acid and trietanolamin on good physical propertie of cream. Cream was made with stearic acid 15% minimum concentration and maximum concentration 17%, triethanolamine with minimum concentration 2% and maximum concentration 4%. The optimization of the formula was using the simplex lattice design method with parameters are pH, viscosity, spreadability, adhesion and protection. The optimum cream formula on the combination of stearic acid 16.7 grams and triethanolamine 2.3 grams. Verification results of optimal formula cream for pH got 6.1, viscosity 237.47, adhesion 12.32, power spread 18.11, protection 14.98 which showed no significant difference in the test, and has good stability. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-09-12 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/44 10.33759/jrki.v1i3.44 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 3 (2019): Jurnal Riset Kefarmasian Indonesia; 225-237 2655-8289 10.33759/jrki.v1i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/44/42 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/46 2019-05-23T09:11:53Z jrki:ART driver

PENETAPAN KADAR FLAVONOID EKSTRAK DAUN KELAKAI (Stenochlaena palustris (Burm. F.) Bedd.) DENGAN METODE SPEKTROFOTOMETRI UV-VIS Syamsul, Eka Siswanto Hakim, Yana Yunita Nurhasnawati, Henny Leaf Kelakai Flavonoid Level Crude Extract Kelakai (Stenochlaena palustris (Burm F.) Bedd.) is a medicinal plant of Borneo. The purpose of this research is to determine the level of flavonoid in crude extract of kelakai leaf by UV-Vis Spectrophotometer. The research was conducted by collection of the kelakai leaves and plant determination. The ethanolic extract of kelakai leaves was collected using macceration methode. The determination of flavonoid level was conducted by UV-Vis Spectrophotometer using quersetin as standard compound. The study showed that the rendemen of crude extract of kelakai leaf was (22,92%). The moisture content in viscous extract was (19,71%). The level of Flavonoids in extract was (2,2159±0,083%). APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-01-11 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/46 10.33759/jrki.v1i1.46 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 1 (2019): Jurnal Riset Kefarmasian Indonesia; 11-20 2655-8289 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/46/2 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/52 2019-09-19T18:37:35Z jrki:ART driver

EVALUASI TINGKAT KEPUASAN PASIEN TERHADAP PELAYANAN KEFARMASIAN DI KLINIK X MENGGUNAKAN APLIKASI E-SERVQUAL BERBASIS WEB Rianto, Leonov Al'Qarana, Gilang Sabrina, Alifa satisfication clinic service application In an effort to improve the quality of service, patient satisfaction can be measured by the SERVQUAL (SERVICE QUALITY) method by making a comprehensive customer satisfaction assessment survey for services in the field of goods and services that prioritize pharmaceutical services. Customer satisfaction analysis is based on five dimensions of service quality, namely responsiveness, reliability, assurance, empathy, and tangible. The formulation of the problem in this study wanted to find out how patient satisfaction with pharmacy services in clinic X. The purpose of this study was to describe patient satisfaction with pharmacy services in clinic X. Using descriptive quantitative methods to determine the level of patient satisfaction with pharmaceutical services using questionnaires as instruments Study data on patient visits were treated at 3 months beginning in 2018 in January 2,970 patients, February 2,868 patients, and March 3,304 patients. Based on data that has been recapitulated in a system by web-based e-SERVQUAL application and its validity has been tested, the percentage of each variable is evenly distributed in the range of 70%, on the dimensions of attitude and appearance. , 20% of patients were satisfied, in the dimension of drug waiting time, 73.90% of patients were satisfied, on the assurance dimension 74.45% of patients were satisfied, on the dimensions of empathy satisfied patients were 73.50%, on the dimensions of facilities and patient facilities were satisfied , 87%. From these results, the patient is satisfied with the overall dimensions of service, the greatest level of satisfaction is in the dimensions of attitude and appearance, and the smallest level of satisfaction is on the dimensions of facilities and facilities, it can be concluded that the percentage of 74.14% is in the predicate satisfied. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-09-12 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/52 10.33759/jrki.v1i3.52 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 3 (2019): Jurnal Riset Kefarmasian Indonesia; 210-224 2655-8289 10.33759/jrki.v1i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/52/41 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/53 2019-09-19T18:27:29Z jrki:ART driver

FORMULASI NANOEMULGEL EKSTRAK KULIT MANGGIS (Garcinia Mangostana L.) Damayanti, Hilda Wikarsa, Saleh Jafar, Garnadi Mangosteen Peel Nanoemulgel Antioxidant Antioxidant-containing cosmetic has antiaging therapy that can inhibit the free radical formation. Mangosteen peel extract has very strong antioxidant activity. To enhance the effect and comfortness of mangosteen peel extract use on the skin, it could be made into nanoemulgel. The article provides the information about method of preparation and evaluation of nanoemulsion-gel. The purpose of this study was to formulate a stable microemulgel of mangosteen peel extractusing halal materials declared halal according to Islamic Shari’a.  the materials used don’t contain carrion, blood, pig and/ animals that don’t conform to Islamic Shari’a. Microemulgel mangosteen peel extract was made by varying plantacare® 1200 UP concentration as cosurfactant (5, 10, 15, 20 and 25%) in the microemulsion and it was incorporated into the gel base. Evaluations were included the antioxidant activity test and organoleptic, pH, viscosity, stability, particle size analysis and panelist test. The antioxidant activity determined by DPPH method showed that IC50 value of mangosteen peel extract was 5.54 ppm. The third microemulsion formula containing cosurfactant of 15% resulted in the best results in that the parameter of the product can be penetrated by ray laser was at particle size of  23.65 nm, was determined by tranmission Electron Microscopy (TEM). Microemulgel containing Viscolam® MAC 10 of seven percent gave the stable formula proofed by freeze thaw and sentrifuga test. The five microemulgel formulations were stable.     APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-08-18 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/53 10.33759/jrki.v1i3.53 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 3 (2019): Jurnal Riset Kefarmasian Indonesia; 166-176 2655-8289 10.33759/jrki.v1i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/53/38 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/54 2019-09-20T04:33:53Z jrki:ART driver

FORMULASI EKSTRAK KLOROFORM DAUN BELIMBING WULUH DALAM BENTUK SEDIAAN GEL dan UJI AKTIVITAS ANTIBAKTERI TERHADAP Staphylococcus epidermidis Tan, Verawaty Rahmadhani, Nova Tri Dewi, Irene Puspa Gel, Belimbing Wuluh leaves (Averrhoa bilimbi L.), Staphylococcus epidermidis. Herbal treatments are needed to treat various diseases, one of which is the leaves of Belimbing Wuluh (Averrhoa bilimbi L.). The aim of this study was to formulate chloroform extract of Belimbing Wuluh’s leaf (Averrhoa bilimbi L.) into gel preparations that were good, effective, and safe to use and to determine the antibacterial activity of chloroform extract of Belimbing Wuluh (Averrhoa bilimbi L.) leaf extract to Staphylococcus epidermidis by well method. The results showed that form of gel is a thick, dark green, the distinctive smell of Wuluh starfruit leaf extract, homogeneous, good skin pH, good washing and does not irritate the skin. This study uses Nutrient Agar media as a culture medium for Staphylococcus epidermidis bacteria. The results indicate that the chloroform extract gel leaves of belimbing wuluh leaves in formula 1 (10%), formula 2 (20%), and formula 3 (30%) were able to inhibit the growth of Staphylococcus epidermidis bacteria. In formula 3 (30%) gel extract of belimbing wuluh leaves has the widest zone of inhibition compared to other dosage formulas. The statistical test using the One Way ANOVA test showed a significant difference from the average diameter of the inhibition zone between all concentrations of chloroform extract gel leaves of belimbing wuluh leaves that were significant with (α ˂ 0.05). APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-09-12 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/54 10.33759/jrki.v1i3.54 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 3 (2019): Jurnal Riset Kefarmasian Indonesia; 203-209 2655-8289 10.33759/jrki.v1i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/54/45 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/55 2019-09-19T19:13:28Z jrki:ART driver

PENENTUAN NILAI SPF EKSTRAK DAN LOSIO TABIR SURYA EKSTRAK ETANOL DAUN KERSEN (Muntingia calabura L.) DENGAN METODE SPEKTROFOTOMETRI UV-VIS Widyawati, Erni Ayuningtyas, Nurista Dida Pitarisa, Agustina Putri kersen leaves sunscreen lotion SPF erythema transmission pigmentation transmission Excessive and prolonged sun exposure can cause erythema and sunburn, premature aging and skin cancer. Kersen leaves contain total flavonoids and phenolics which can be used as active ingredients for making sunscreen lotion. This study was to determine the SPF value, the value of erythema transmission (% Te) and the value of pigmentation Transmission (% Tp) from extracts and lotions of kersen ethanol extract using the Uv-Vis spectrophotometric method. Absorbance increases at wavelengths of 290-400 nm at intervals of 5 nm. The results showed SPF extract values ​​with a composition of 500 ppm, 1000 ppm, and 2000 ppm combined - 12 were 12.15 (maximum ability); 17,29 (ultra protection); and 22.01 (ultra protection). % Te value 0.54; 0.16 and 0.05 all include the total block category,% value Tp 2.50; 1.30 and 0.49 (total blocks). Whereas for losio with a concentration of 0.5%, 1% and 2% respectively the SPF value produced is 3.61 (minimum protection); 8.18 (maximum protection) and 10.13 (maximum protection). % Te value 4.29 (extra protection); 1.58 (extra protection) and 0.99 (maximum protection). % value Tp 9.30; 4.22 and 2.80 are all included in the total block category. Keywords :  kersen leaves, sunscreen lotion, SPF, erythema transmission, pigmentation transmission APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-09-18 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/55 10.33759/jrki.v1i3.55 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 3 (2019): Jurnal Riset Kefarmasian Indonesia; 189-202 2655-8289 10.33759/jrki.v1i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/55/44 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/57 2020-01-31T09:37:08Z jrki:ART driver

ISOLASI DAN UJI AKTIVITAS DAYA HAMBAT EKSTRAK ETANOL BIJI PINANG (Areca catechu L.) TERHADAP BAKTERI PADA LIDAH Djohari, Meiriza Putri, Wulandari Yulia Pratiwi, Erniza Antibakteri, Ekstrak, Biji Pinang, Lidah Betel  nut (Areca catechu L.) is a natural material that has antibacterial activity in treating diseased on teeth, halitosis and can inhibit of dental caries. The objective of this research is type of bacteria based on morphology, the results of bacterial identification tests on the tongue and to determine the effect of the inhibitory power of betel nut ethanol extract (Areca catechu L.) to bacteria of the tongue. Antibacterial activity testing using disc diffusion method with various concentrations of 10%, 20% and 30%. Secondary metabolite contents  are alkaloid, terpenoid and flavonoid.The results obtained from the identification test based on the color of bacteria Branhamella catarrhalis, Staphylococcus epidermidis and Straphylococcus aureus. Ethanol extract of areca nut (Areca catechu L.) is better to inhibiting the growth of Staphylococcus epidermidis and Staphylococcus aureus compared to Branhamella catarrhalis. Based on Two Way Anova statistical data on inhibitory zone diameters, there were differences between the concentration groups of 10%, 20% and 30% and there were significant differences in the inhibitory activity of Branhamella catarrhalis bacteria compared to Staphylococcus epidermidis and Straphylococcus aureus bacteria but not significantly different between Staphylococcus epidermidis and Straphylococcus aureus bacteria APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2019-09-12 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/57 10.33759/jrki.v1i3.57 Jurnal Riset Kefarmasian Indonesia; Vol. 1 No. 3 (2019): Jurnal Riset Kefarmasian Indonesia; 177-188 2655-8289 10.33759/jrki.v1i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/57/61 Copyright (c) 2019 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/62 2020-01-29T13:04:59Z jrki:ART driver

FORMULASI DAN EFEKTIFITAS SAMPO EKSTRAK BUAH PEDADA (Sonneratia caseolaris L) SEBAGAI ANTIKETOMBE TERHADAP Candida albicans Sambodo, Dwi Kurniawati Yani, Lisa Erie Antidandruff Pedada Fruit Candida albicans      Half of the world's population has been affected by dandruff, especially those aged 15 to 50 years. Dandruff is one of the problems on the scalp with common symptoms of scales (exfoliation of dead skin), itching of the scalp and redness around the scalp. Dandruff can be caused by an oily scalp, hormones or fungus. One of the fungi that cause dandruff is Candida albicans. Based on research that has been done, secondary metabolite compounds of methanol extract of peada fruit peel which is a pure white compound in the form of powder are identified as alkaloid compounds. In general, alkaloids can be used as an antifungal. Anti-dandruff shampoo is a dosage that is often used daily and can be used to treat and prevent scalp from excessive dandruff where this shampoo contains active antifungal agents which are effective as an anti-dandruff. Pedada fruit was extracted using multilevel maceration method with methanol as a solvent. Pedada fruit extract shampoo is formulated with variations in extract concentration into 3 formulas. Shampoo was tested for physical properties and effectiveness of anti-dandruff using the Kirby-Bauer Diffusion method with PDA media. From the results obtained it can be concluded that the physical properties of the three formulas of pedada fruit extract shampoo (Sonnerratia caseolaris L) include organoleptic, pH , high foam , cycling test, and viscosity produced good physical properties in accordance with the standard test of the physical properties of shampoo, however Homogeneity test results show that formula III shampoo is less homogeneous. All three shampoo formulas are effective as anti-dandruff against the fungus Candida albicans. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2020-01-15 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/62 10.33759/jrki.v2i1.62 Jurnal Riset Kefarmasian Indonesia; Vol. 2 No. 1 (2020): Jurnal Riset Kefarmasian Indonesia; 1-9 2655-8289 10.33759/jrki.v2i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/62/58 Copyright (c) 2020 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/64 2020-01-29T13:04:59Z jrki:ART driver

PENGUKURAN TEKANAN DARAH PADA PASIEN GAGAL JANTUNG KONGESTIF DI INSTALASI RAWAT INAP RUMAH SAKIT ST. ELISABETH SEMARANG Rukminingsih, Fef Susanto, Theresia Carolina Gagal Jantung Kongestif Tekanan Darah RS St. Elisabeth Semarang Congestive heart failure (CHF) is one of the top 10 diseases in the Inpatient of. St. Elisabeth Hospital Semarang. The main cause of CHF is hypertension. CHF patients receive antihypertensive therapy to control their blood pressure. This study aims to determine the decrease in blood pressure of CHF patients and the suitability of blood pressure of CHF patients with their treatment targets according to the Eighth Joint National Committee (JNC VIII) at the Inpatient Installation of St. Elisabeth Hospital Semarang. This research is an observational descriptive study, using retrospective data. Data was taken from medical records of CHF patients in inpatients who received antihypertensive therapy for the period October - December 2017, 40 years or older, with or without concomitant diseases. Based on the results of tracing of medical records it is known that the number of CHF patients who met the inclusion criteria was 60 people, consisting of 30 male patients and 30 female patients. A total of 35 patients (58.33%) were aged over 60 years. A total of 19 patients had concomitant diabetes mellitus type 2 and / or chronic kidney failure. A total of 51 patients (85%) during hospitalization experienced an average reduction in systolic BP of 21.65 mmHg and as many as 37 patients (61.67%) experienced an average reduction in diastolic BP of 13.38 mmHg. The suitability of the patient's blood pressure when leaving the hospital with the target blood pressure according to JNC VIII is 81.67%. Thus the progression of cardiac deterioration in most CHF patients can be inhibited. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2020-01-15 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/64 10.33759/jrki.v2i1.64 Jurnal Riset Kefarmasian Indonesia; Vol. 2 No. 1 (2020): Jurnal Riset Kefarmasian Indonesia; 10-16 2655-8289 10.33759/jrki.v2i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/64/57 Copyright (c) 2020 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/66 2020-01-29T13:04:59Z jrki:ART driver

AKTIVITAS ANTIBAKTERI EKSTRAK PERASAN DAUN MENGKUDU (Morinda citrifolia L.) TERHADAP Escherichia coli SECARA IN VITRO Priamsari, Margareta Retno Wibowo, Agastia Cicilia Noni juice extract, Escherichia coli, Disc Diffusion, MIC Noni juice can inhibit the growth of Escherichia coli bacteria. Noni juice extraction needs concentration to extract so that the preparation is more stable in the storage process. The purpose of this study was to determine the antibacterial activity and the amount of the minimum inhibitory concentration of noni juice extract from E. coli bacteria in vitro. This type of experimental research with a completely randomized one-way design. The extract was obtained by concentrating the Noni leaf extract. Extract quality control parameters include organoleptic, yield, drying shrinkage, and qualitative tests of flavonoid and anthraquinone compounds. Antibacterial activity test using the disc diffusion method with an extract concentration of 1.56%; 3.12%; 6.25%; 12.5%; and 25% with 3 replications. Positive control of amoxicillin and negative control of distilled water. Inhibition is known from the zone formed around the paper disc. The data obtained were statistically analyzed using Kruskall Wallis followed by Mann Whitney with a 95% confidence level. The results showed that the variation in the concentration of the noni juice extract had a significant effect (p <0.05). The biggest inhibitory zone was seen at 25% concentration of 10.16 mm and included in the strong category. The minimum inhibitory power was produced at a concentration of 3.12% at 2.50 mm with a weak treatment category. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2020-01-16 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/66 10.33759/jrki.v2i1.66 Jurnal Riset Kefarmasian Indonesia; Vol. 2 No. 1 (2020): Jurnal Riset Kefarmasian Indonesia; 26-34 2655-8289 10.33759/jrki.v2i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/66/55 Copyright (c) 2020 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/70 2020-01-29T13:04:59Z jrki:ART driver

UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN SURUHAN (Peperomia pellucida L. Kunth) TERHADAP Propionibacterium acnes PENYEBAB JERAWAT Yufiradani, Yufiradani Mayefis, Delladari Marliza, Hesti Peperomia pellucida L. Kunth antibacterial Propionibacterium acnes acne Acne is one of the most common skin diseases that occur at all ages, especially in adolescents who are just experiencing puberty. One of the plants that has antibacterial properties is the leaves of suruhan. However untill now not found research of suruhan leaf used as an acne medicine. The aim of this study was to determine the antibacterial activity of suruhan leaf extracts on the growth of Propionibacterium acnes. The method used is disc diffusion by given 5 treatments starting with a concentration of 15%, 20%, 25%, positive control of clindamycin and negative control of aquadest.. The results obtained from leaf extracts were able to inhibit the growth of P. acnes bacteria in various concentrations. Suruhan leaf extracts at a concentration of 25% showed response resistance was greater than other concentrations. The one way Anova SPSS test showed p <0.05 which means that there were differences in the inhibitory concentration of various extracts on the growth of P. acnes that cause acne APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2020-01-16 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/70 10.33759/jrki.v2i1.70 Jurnal Riset Kefarmasian Indonesia; Vol. 2 No. 1 (2020): Jurnal Riset Kefarmasian Indonesia; 35-41 2655-8289 10.33759/jrki.v2i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/70/53 Copyright (c) 2020 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/72 2020-09-24T08:29:47Z jrki:ART driver

UJI AKTIVITAS SITOTOKSIK EKSTRAK METANOL BUAH KETUMBAR (Coriandrum sativum Linn) TERHADAP ARTEMIA SALINA LEACH DENGAN UJI BSLT (Brine Shrimp Lethality Test) Yulia, Mega Anggraini, Rani Farizal, Farizal Ketumbar Coriandrum sativum Sitotoksik BSLT Coriander is a common herb can be used as traditional medicine. One of the expected benefits of Coriander fruits is an anti-cancer. This study aims to determine the cytotoxic activity of Coriander extract (Coriandrum sativum Linn) on shrimp larvae (Artemia salina Leach) with the BSLT (Brine Shrimp Lethality Test) method. Coriander fruits was extracted using methanol solvent and maceration method, then concentrated it with a rotary evaporator until a thick extract. Cytotoxic activity test used methanol extract with several concentration : 1,000 ppm, 100 ppm, 10 ppm, and 1 ppm. The result of this research reveal that methanol extract of Coriander fruits has cytotoxic activity with LC50 value is 32.35 ppm. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2020-09-16 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/72 10.33759/jrki.v2i3.72 Jurnal Riset Kefarmasian Indonesia; Vol. 2 No. 3 (2020): Jurnal Riset Kefarmasian Indonesia; 137-146 2655-8289 10.33759/jrki.v2i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/72/74 Copyright (c) 2020 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/73 2020-05-30T05:48:42Z jrki:ART driver

AKTIVITAS ANTIBAKTERI EKSTRAK AIR KULIT BAWANG MERAH (Allium cepa L.) TERHADAP BAKTERI Propionibacterium acnes Sa`adah, Hayatus Supomo, Supomo Musaenah, Musaenah Aktivitas Antibakteri Propionibacterium acnes bawang merah (Allium cepa L.) Propionibacterium acnes is one of the causes of acne. Shallot peels contain flavonoids, tannins, and saponins which potentially have antibacterial activity. The purpose of this study was to determine whether the water extracts of shallot peels have antibacterial activity against Propionibacterium acnes and determine the concentration which can inhibit the growth of bacteria Propionibacterium acnes. This research is an experimental study. The research stage begins with the extraction of shallot peels using in the foundation. Antibacterial activity was tested using the diffusion method with the Cup-plate technique. Propionibacterium acnes used as a sample of bacteria, with extract concentrations of 5%, 10%, 20%, and 40%. Positive controls used are clindamycin 150 mg and negative controls were used dimethyl sulfoxide 1% (v / v). Data were analyzed with a statistical test of the Kolmogorov-Smirnov method. The measurement results inhibition zone of shallot peels water extract with a concentration of 5%, 10%, 20%, and 40% of the bacteria Propionibacterium acnes sequentially by 12.8 mm, 13 mm, 14.33 mm and 15.50 mm in the strong category. The measurements of bacterial growth inhibition zone were statistically analyzed with the Kruskal-Wallis method gained 0,053 results indicating that the test has a significant effect (P > 0.05) with a decision that means that there is no significant difference between all concentrations. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2020-05-02 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/73 10.33759/jrki.v2i2.73 Jurnal Riset Kefarmasian Indonesia; Vol. 2 No. 2 (2020): Jurnal Riset Kefarmasian Indonesia; 80-88 2655-8289 10.33759/jrki.v2i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/73/68 Copyright (c) 2020 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/74 2020-01-29T13:04:59Z jrki:ART driver

FORMULASI DAN UJI SIFAT FISIK MASKER ANTIJERAWAT DARI EKSTRAK SABUT KELAPA ( Cocos nucifera L) Fauziah, Fauziah Marwarni, Rima Adriani, Azmalina Sabut Kelapa, Tanin, Masker, Jerawat, Uji Sifat Fisik Coconut is a multipurpose tree for people in the tropics. Almost all parts can be used such as leaves, fruit, stems, and roots. Besides having many benefits of coconut, it also produces waste from its fruit, namely coconut fiber. Coconut coir has a very high tannin content. In general, tannin compounds can be indicated as anti-inflammatory, and anti-bacterial. The purpose of this study was to formulate the anti-acne mask from coconut coir extract and to test its physical properties. This study uses an experimental research method, in which three mask formulas are made with variations in the concentration of active substances and polyvinyl alcohol (PVA). In this study the active substance used was coconut coir extract. The formulas used are formulas A, B, and C with the concentration of active substances successively as follows: 1%, 2%, 4%. The results of research that have been carried out that the mask formula that has the best physical properties is formula B, because it fulfills the physical properties provisions of the peel off face mask including organoleptic, homogeneity, pH, dispersal power, and drying time. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2020-01-20 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/74 10.33759/jrki.v2i1.74 Jurnal Riset Kefarmasian Indonesia; Vol. 2 No. 1 (2020): Jurnal Riset Kefarmasian Indonesia; 42-51 2655-8289 10.33759/jrki.v2i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/74/54 Copyright (c) 2020 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/77 2020-05-30T05:48:42Z jrki:ART driver

KAJIAN PERESEPAN OBAT ANTIHISTAMIN PADA PASIEN RAWAT JALAN DI SALAH SATU RUMAH SAKIT DI BANDUNG Lisni, Ida Anggriani, Ani Puspitasari, Regina Histamin, Antihistamin, Interaksi, Retrospektif Histamine is one of the factors that cause acute and chronic disorders, so it is necessary to investigate further the mechanism of antihistamines in the treatment of allergic diseases. Antihistamines are substances that can reduce or block the effects of histamine on the body by blocking histamine receptors. Antihistamines are one of the drugs that are often prescribed to children to the elderly. Thus the application of therapy in medicine is needed to ensure the use of appropriate drugs to prevent the occurrence of medication errors so that the goal of therapeutic effectiveness can be achieved. The purpose of this study was to determine the prescribing pattern of antihistamine drugs and assess the accuracy of the administration of antihistamines based on dose accuracy and potential drug interactions. Prescribing studies of this drug are descriptive quantitative and qualitative by using data sources in the form of patient prescription sheets taken retrospectively. The results of quantitative research data show that patients 57.23% were female, the highest age was 55-59 years old 12.26%, the most widely used drug was setirizine 72.48%, dose accuracy 89.60% and more doses 10.40%, the potential for drug interactions occurred in 27.83%, The drug that has the most potential for interaction is setirizine with theophylline. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2020-05-01 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/77 10.33759/jrki.v2i2.77 Jurnal Riset Kefarmasian Indonesia; Vol. 2 No. 2 (2020): Jurnal Riset Kefarmasian Indonesia; 52-62 2655-8289 10.33759/jrki.v2i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/77/62 Copyright (c) 2020 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/79 2020-05-30T05:48:42Z jrki:ART driver

PEMANFAATAN POTENSI LIMBAH KULIT BAWANG MERAH (Allium Cepa. L) SEBAGAI SEDIAAN GEL HAND SANITIZER Usman, Yusnita Keywords : Red Onion Skin, Hydroxy Ethyl Cellulose, Physical Stability, Gel             The increased health problems caused by microorganisms at the hands, hand sanitizer gel as the way out to maintained health and hand hygiene because it is more practical and easy to carry. The purpose of this study was to make formulations of gel with physically stable and had inhibitory activity against the Staphylococcus aureus bacteria. In this study three formulations were made with a ratio of Hydroxy ethyl selilulose 0.5% (F1), 1% (F2) and 2% (F3) then physical stability testing included organoleptic, homogeneity, pH and dispersion before and after accelerated storage, then antimicrobial activity by sump method. Organoleptic test showed there is no color, smell and texture changes. The results of the homogenety test, formula with concentration of Hydroxy ethyl cellulose 1% and 2% is homogeneous. The pH test results showed that the gel preparation did not change pH. Dispersing test showed concentration hydroxyethyl cellulose 1% has the highest dispersion value. but statistical paired T test results showed that the dispersion before and after storage was accelerated significantly different 0.043 (p <0.05), but still in accordance with the range of dispersion specifications for a good semisolid preparation.The MIC test results showed Formulation F1, F2 and F3 ethanol extract red onion skin gel are strong  inhibitory effect, ethanol extract of red onion skin gel F1 inhibitory zone is 16mm, F2 and F3 had the same inhibitory zone is 14.33. It can be concluded F2  has the best physical stability, but F1  is the most effective to inhibit Staphylococcus aureus.     APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2020-05-01 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/79 10.33759/jrki.v2i2.79 Jurnal Riset Kefarmasian Indonesia; Vol. 2 No. 2 (2020): Jurnal Riset Kefarmasian Indonesia; 63-71 2655-8289 10.33759/jrki.v2i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/79/63 Copyright (c) 2020 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/81 2020-05-30T05:48:42Z jrki:ART driver

GAMBARAN PEMBERIAN OBAT PADA PENDERITA HIPERTENSI DI PUSKESMAS RAWANG Taslim, Tuty Betris, Yani Anggela Hipertensi Retrospektif Puskesmas Rawang Hypertension is a disease that often causes death because many people do not realize it. People have hypertension if the blood pressure above 140/90 mmHg after regular checking. In Puskesmas Rawang, hypertension is the second-highest disease. This study aims to overview drug administration in patient's hypertension. This research is an observational descriptive study using retrospective data with the inclusion criteria. Data was taken from the recipes in April till June 2019 period. Based on the research, 82 % of women more suffer than men. While the age criteria from  41 – 61 years was 53.8%. The majority of drugs were given in Puskesmas Rawang was amlodipine with a percentage of 89%. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2020-05-02 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/81 10.33759/jrki.v2i2.81 Jurnal Riset Kefarmasian Indonesia; Vol. 2 No. 2 (2020): Jurnal Riset Kefarmasian Indonesia; 72-79 2655-8289 10.33759/jrki.v2i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/81/64 Copyright (c) 2020 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/82 2020-05-30T05:48:42Z jrki:ART driver

EVALUASI PERESEPAN PADA PASIEN GERIATRI DI KLINIK PENYAKIT DALAM INSTALASI RAWAT JALAN RSUD K.R.M.T WONGSONEGORO SEMARANG Mulyani, Tri Rukminingsih, Fef Geriatri Polifarmasi Beers Criteria The medical problems encountered in geriatric patients cause the prescribing to be susceptible to polypharmacy so that the possibility of creating Drug Related Problems (DRPs) is likely. Beers Criteria is one method to avoid the occurrence of DRPs. This study aims to evaluate prescribing of geriatric patients based on the Beers Criteria 2015 at the internal medicine clinic in the outpatient installation of K.R.M.T Wongsonegoro Hospital Semarang. This research was an descriptive observational study using retrospective data from geriatric patients' medical records at the internal medicine clinic in the outpatient installation of K.R.M.T Wongsonegoro Hospital Semarang in the period October - December 2017. A total of 300 medical records were taken at simple random as samples. Data for each patient were only taken once during the study period. The patient is a national health insurance participant and is ≥60 years old. The data obtained was then identified using Beers Criteria 2015. Based on the prescription of 300 geriatric patients in the internal medicine clinic in Wongsonegoro Hospital Semarang, it is known that 88,33% patients received prescription included in Beers Criteria 2015. The five medicine most prescribed are Na diclofenac, omeprazole, digoxin, ranitidine, and diazepam. Medications included in Beers Criteria are medicine that should not be given to geriatric patients so that caution is needed in the use of these medicine. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2020-05-14 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/82 10.33759/jrki.v2i2.82 Jurnal Riset Kefarmasian Indonesia; Vol. 2 No. 2 (2020): Jurnal Riset Kefarmasian Indonesia; 89-96 2655-8289 10.33759/jrki.v2i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/82/69 Copyright (c) 2020 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/84 2020-06-01T15:31:10Z jrki:ART driver

EFEKTIVITAS GEL EKSTRAK ETANOL BAWANG PUTIH (Allium sativum L.) TERHADAP BAKTERI Staphylococcus aureus Dewi, Irene Puspa Orde, Ilham Maslan Verawaty, Verawaty Gel, Bawang putih (Allium sativum L.), Staphylococcus aureus, antibakteri. Garlic (Allium sativum L.) is one of the traditional medicines which has an antibacterial efficacy compound namely Allisin which is able to inhibit the growth of Staphylococcus aureus bacteria. This study aims to formulate the garlic bulb extract into a good gel preparation for use as an acne drug and to determine the antibacterial effectiveness of the ethanol extract of garlic gel against the bacterium Staphylococcus aureus using the wells method. The gel evaluation was carried out to meet the requirements with organoleptic test parameters, homogeneity, pH, spreadability, adhesion and irritation test. This study uses extracts of 10% and 20% concentrations, at each concentration being able to inhibit the growth of Staphylococcus aureus bacteria. In the formula, the concentration of 20% has a inhibition zone diameter of 1.59 cm and a concentration of 10% has a inhibition of 1.50 cm. Statistical test results using the One Way ANOVA test found that there was no significant difference between the average diameter of inhibition of garlic extract gel concentration of 10% with a concentration of 20%. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2020-05-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/84 10.33759/jrki.v2i2.84 Jurnal Riset Kefarmasian Indonesia; Vol. 2 No. 2 (2020): Jurnal Riset Kefarmasian Indonesia; 105-112 2655-8289 10.33759/jrki.v2i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/84/71 Copyright (c) 2020 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/85 2020-05-30T05:48:42Z jrki:ART driver

PERBANDINGAN EKSTRAK LAMUR Aquilaria malaccensis DENGAN METODE MASERASI DAN REFLUKS Syamsul, Eka Siswanto Amanda, Nadhila Ajrina Lestari, Dwi Aquilaria malaccensis Lamk maceration and reflux method, yield Gaharu (Aquilaria malaccensis Lamk) is a plant of the thymelaeaceae family that is widely used by the people of West Kutai Regency as a medicinal plant for skin wounds, diabetes, asthma, stomach pain and sleep disorders, aromatherapy and used as ingredients for perfume because it has a distinctive aroma. The extraction process will determine how much yield is produced. This study aims to determine the percent (%) yield of agarwood leaf ethanol extract using maceration and reflux methods. The research stage includes plant determination, sample processing, extraction using maceration and reflux methods with 70% ethanol solvent, determination of the yield and phytochemical screening. Data analysis in the form of descriptive data analysis and presented in tabular form. The results showed that the reflux method produced a higher average yield of 30.70% and maceration method of 29.97%. Statistical test results using the Independent Sample T-Test method showed that there was no significant difference in the yield produced from the maceration and reflux method because (p> 0.05). Phytochemical screening test results showed that agarwood leaf extract contains flavonoids, tannins, saponins and steroids APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2020-05-18 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/85 10.33759/jrki.v2i2.85 Jurnal Riset Kefarmasian Indonesia; Vol. 2 No. 2 (2020): Jurnal Riset Kefarmasian Indonesia; 97-104 2655-8289 10.33759/jrki.v2i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/85/70 Copyright (c) 2020 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/88 2020-05-31T07:32:17Z jrki:ART driver

EFEKTIFITAS PAPARAN SINAR UV DAN ALKOHOL 70% TERHADAP TOTAL BAKTERI PADA UANG KERTAS YANG BEREDAR DI MASA PANDEMI COVID-19 Elisanti, Alinea Dwi Ardianto, Efri Tri Ida, Novita Cholifah Hendriatno, Eryk Alcohol; Dilution Agar; Folding Money; UV light; Swab test. Corona virus disease (COVID-19) has become a global pandemic in the world. Indonesia has declared this pandemic as a national disaster. Positive cases and deaths have increased every day. This was a long list of the effects of the COVID-19 pandemic on life. Several solutions have been designed to prevent the rapid transmission of this virus, one of them was by making sterilizer and hand sanitizer products. But there was still debate regarding the effectiveness of the use of UV rays and antiseptics as hygiene products offered.So we need a study to determine the effectiveness of UV exposure and the use of antiseptics to kill germs. This study used an experimental design, the sample used was in the form of folding money taken by the bacteria and grown on the media so that were classified into 3 groups, namely without treatment, 70% alcohol treatment and 10 seconds UV light treatment. The samples were analyzed using the dilution agar method and swab test with two repetitions. The results showed the average number of colony forming units (cfu) of bacteria using the dilution test method and swab test methode were 419 cfu on without treatment group; 4 cfu on alcohol 70% ; and 150 cfu on UV light (10 seconds). The alcohol 70% was more effective than 10 seconds UV light exposure to reduce the amount of bacterial cfu on folding money. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2020-05-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/88 10.33759/jrki.v2i2.88 Jurnal Riset Kefarmasian Indonesia; Vol. 2 No. 2 (2020): Jurnal Riset Kefarmasian Indonesia; 113-121 2655-8289 10.33759/jrki.v2i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/88/72 Copyright (c) 2020 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/89 2020-09-25T10:04:17Z jrki:ART driver

KAJIAN PUSTAKA FORMULASI DAN EVALUASI MIKROKAPSUL SALUT ENTERIK MENGGUNAKAN ACRYL-EZE® & SURETERIC DENGAN METODE PENGGABUNGAN MIKROENKAPSULASI DENGAN EKSTRUSI-SFERONISASI Santoso, Rahmat Aliudin, Fiqi Ekstrusi-sferonisasi, Mikroenkapsulasi, Salut enterik Microcapsules were prepared by means of microencapsulation modified by the extrusion-spheronization method. The extrusion-spheronization method is used to cover the shortcomings of the microencapsulation method. The results showed that Acryl-eze and Sureterik can be used in coatings in producing microcapsules. The results of research evaluating the formulation of enteric acetosal coated microcapsules have not resulted in delayed release system that is in accordance with monographic requirements and dissolution profile testing has not shown the elimination stage. The results of the evaluation of the delayed release release system enteric coated microcapsule formulation met the requirements of monograph and dissolution profile test results, except for F3 in buffering conditions. The purpose of this literature review is to examine the enteric-coated microcapsule formulation using Acryl-eze® & Sureteric by combining microencapsulation and spheronization extrusion methods. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2020-09-15 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/89 10.33759/jrki.v2i3.89 Jurnal Riset Kefarmasian Indonesia; Vol. 2 No. 3 (2020): Jurnal Riset Kefarmasian Indonesia; 122-136 2655-8289 10.33759/jrki.v2i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/89/73 Copyright (c) 2020 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/97 2020-09-24T08:29:47Z jrki:ART driver

KEGIATAN FARMAKOLOGIS DARI BERBAGAI BAGIAN Carica papaya Linn. EKSTRAK: BUAH, DAUN, BENIH, UAP, KULIT DAN AKAR Hidayati, Tita Kosima Susilawati, Yasmiwar Muhtadi, Ahmad Carica papaya Linn Carica papaya (Caricaceae) Linn. (CP) is a popular tropical plant which provide a huge benefit. The fruit is either delicious and healthy while other parts have a great potential medicinal properties. CP are classified as plants that have anti-microbial activity, anti oxidant, anti malaria, anti-ulcer, anti-HIV, anti-inflammatory, anti-cancer, anti-hypertension, anti-fertility, anti-fungal and anti diabetic. Pharmacological activity of papaya plants related to the content of phytochemical  compounds of alkaloid, flavonoid , tannin, saponin, enzyme: papain and chymopapain. These phytochemical  content have been found in the young leaf, stem bark, dry seeds. Papaya leaf reveal more pharmacologycal activities because that have wide variety of phytochemical contents. In this review will be studied pharmacologycal activities  of Carica papaya Linn. extract that  obtained from fruit, leaf, seeds, stem bark and root. Besides, their  various phytochemical contents are also described.  APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2020-09-17 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/97 10.33759/jrki.v2i3.97 Jurnal Riset Kefarmasian Indonesia; Vol. 2 No. 3 (2020): Jurnal Riset Kefarmasian Indonesia; 211-226 2655-8289 10.33759/jrki.v2i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/97/79 Copyright (c) 2020 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/98 2020-09-24T08:29:47Z jrki:ART driver

PENETAPAN RENDEMEN EKSTRAK DAUN JAMBU MAWAR (Syzygium jambos L. Alston) BERDASARKAN VARIASI KONSENTRASI ETANOL DENGAN METODE MASERASI Syamsul, Eka Siswanto Anugerah, Olanda Supriningrum, Risa Syzygium jambos, Yield Ethanol concentration Syzygium jambos is a medicinal plant. This study aims to determine the effect of variations in ethanol concentration on yield of guava leaf extract by maceration method. The research conducted was experimental research. The research phase includes sample collection, determination, manufacture of simplicia, extraction by maceration with variations in ethanol concentration, determination of yield, phytochemical screening and determination of drying losses. Phytochemical screening results showed that 50% of ethanol extracts of positive rose guava contained flavonoids, tannins, saponins and steroids / terpenoids, 70% ethanol and 90% positives contained flavonoids, tannins and steroids / terpenoids. The yield of rose guava ethanol extract was 50% (23.01% ± 0.372), 70% ethanol (21.96% ± 1.181) and 90% ethanol (16.57% ± 0.384). LSD test results showed a significant difference (p <0.05) between the 90% to 50% and 70% groups. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2020-09-17 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/98 10.33759/jrki.v2i3.98 Jurnal Riset Kefarmasian Indonesia; Vol. 2 No. 3 (2020): Jurnal Riset Kefarmasian Indonesia; 147-157 2655-8289 10.33759/jrki.v2i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/98/75 Copyright (c) 2020 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/101 2020-09-24T08:29:47Z jrki:ART driver

STUDI ETNOBOTANI TUMBUHAN OBAT BERBASIS PENGETAHUAN LOKAL DI DESA SELOLIMAN KECAMATAN TRAWAS KABUPATEN MOJOKERTO JAWA TIMUR Nurrosyidah, Iif Hanifa Riya, Milu Asri Ma’ruf, Alfian Fachruddin Etnobotani Seloliman Trawas Mojokerto Indonesia is the country with the second largest biodiversity after Brazil, where 20,000 species of medicinal plants in which 1,000 species have been documented and 300 species have been used as traditional medicine. Seloliman is a village located on the slopes of Mount Penanggungan, Trawas District, Mojokerto Regency, East Java. The people of Seloliman village still depend on nature, most people still use natural materials for treatment and daily needs. Therefore in this research ethnobotany study and identification of medicinal plants based on local knowledge will be conducted in Seloliman Village, Trawas District, Mojokerto Regency, East Java. The study was conducted by exploring the potential of the community as a place of ethnobotany research with open observation and interview methods. The technique for selecting informants is based on information from local residents or village heads who are most aware of medicinal plants. Collecting data on medicinal plants used for traditional medicine through structured interviews. Data recorded are local names, Latin names, family names, ways of obtaining, parts of plants used, diseases treated, and how they are used. Furthermore, each type of plant used is documented. Based on the results of research conducted is the type of plant used for treatment varies greatly, the plant parts used are mostly the leaves (57%), flowers (10%), and the rest are the stem, bark, rhizome, roots, flowers, fruit and seeds. Sources of plants used are mostly cultivated plants (46%), wild (30%), wild and cultivated (17%) and bought on the market (7%). While the way to use it is mostly boiled. Most of the Seloliman village community, Trawas Subdistrict, Mojokerto Regency, East Java have been influenced by outside cultures, so that their local knowledge about plants used in medicine needs to be further explored in order to be preserved. There are only two speakers (traditional healers) in the village of Seloliman who still hold the tradition related to treatment using natural materials. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2020-09-17 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/101 10.33759/jrki.v2i3.101 Jurnal Riset Kefarmasian Indonesia; Vol. 2 No. 3 (2020): Jurnal Riset Kefarmasian Indonesia; 169-185 2655-8289 10.33759/jrki.v2i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/101/76 Copyright (c) 2020 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/102 2020-09-24T08:29:47Z jrki:ART driver

PENGARUH LAMA WAKTU FERMENTASI KOMBUCHA ROSELA (Hibiscus sabdariffa L.) TERHADAP AKTIVITAS ANTIBAKTERI Escherichia coli Cholidah, Adinda Ismu Danu, Dwi Nurrosyidah, Iif Hanifa Kombucha Antibakteri Bunga Rosela Roselle flower (Hibiscus sabdarifa L.) is one of the medicinal plants which is often used as traditional medicine.  Roselle flower (Hibiscus sabdarifa L.) contains phenolic compounds such as tannins, saponins and flavonoids that are as antibacterial.  Roselle flower (Hibiscus sabdarifa L.) can be made as a kombucha tea. Kombucha ia useful as an antibacterial, anticancer, improves liver function, anticholesterol, detoxification, improves the digestive system and maintains stamina. The purpose of this research were to find out  the effect of kombucha roselle (Hibiscus sabdarifa L.) fermentation time against antibacterial activity of Escherichia coli. Kombucha roselle made by fermenting roselle stew, starter 10% and sugar 10% for 1 day, 3 days, 5 days, 7 days, 9 days, 11 days, 13 days and 15 days. Then, testing the effectiveness of antibacterial by method Cup-plate technique. The results showed that fermentation of kombucha rosella was able to inhibit the growth of Escherichia coli bacteria with different results according to the length of fermentation time. The results of data analysis using spearman test showed the fermentation time were take effect on e.coli antibacterial activity and continued with Mann Whitney test showed the fermentation of kombucha roselle has a significant inhibitory effect on bacterial growth. The most optimum inhibitory zone in inhibiting Escherichia coli is 15 days fermentation of kombucha roselle for 21,5 mm wich is categorized as very strong antibacterial activity. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2020-09-17 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/102 10.33759/jrki.v2i3.102 Jurnal Riset Kefarmasian Indonesia; Vol. 2 No. 3 (2020): Jurnal Riset Kefarmasian Indonesia; 186-210 2655-8289 10.33759/jrki.v2i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/102/78 Copyright (c) 2020 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/103 2021-05-26T13:32:36Z jrki:ART driver

PENGARUH IKLAN OBAT FLU DI TELEVISI TERHADAP PERILAKU SWAMEDIKASI Mardiati, Nurul Islamiyah, Robiatul Fitriah, Rahmayanti Iklan Obat, Swamedikasi Flu, Kecamatan Karang Intan The high prevalence of flu and the easy availability of drugs in the market and at relatively affordable prices are one of the driving forces for self-medicating by the community. In addition, increasingly sophisticated technological advances make it easy for people to get information, one of which is drug advertisements on television that can influence consumer behavior in the selection of drugs used in self-medication. This research was conducted with the aim of knowing the effect of cold medicine advertisements on television on self-medication behavior in the community of Karang Intan District. This research method is a descriptive observational study with a cross sectional design. The sampling technique was carried out using non-random sampling method, namely accidental sampling, and the number of respondents was 100 people. The data collected comes from questionnaire data, which is filled in by respondents accompanied by researchers. Descriptive data analysis was performed by using the chi square test. The results showed that the effect of cold medicine advertisements on television on self-medicated behavior in the community of Karang Intan District has a significant p value of 0.000. The conclusion is that the advertisement of cold medicine on television has an influence on self-medication behavior in the community of Karang Intan District. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2021-01-16 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/103 10.33759/jrki.v3i1.103 Jurnal Riset Kefarmasian Indonesia; Vol. 3 No. 1 (2021): Jurnal Riset Kefarmasian Indonesia; 35-44 2655-8289 10.33759/jrki.v3i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/103/85 Copyright (c) 2021 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/104 2020-09-24T08:29:47Z jrki:ART driver

EFEKTIVITAS EKSTRAK ETANOL DAUN KIRINYUH (CHROMOLAENA ODORATA L) SEBAGAI ANTIBAKTERI SALMONELLA TYPHI DAN STAPHYLOCOCCUS AUREUS Fadia, Fadia Nurlailah, Nurlailah Helmiah, Tini Elyn Lutpiatina, Leka Chromolaena odorata L.; Salmonella typhi; Staphylococcus aureus         Salmonella typhi and Staphylococcus aureus are pathogenic bacteria that cause infectious diseases. Treatment of these diseases can be done by giving antibacterial drugs. One of the plants that can be used as an antibacterial drug is the leaves of Chromolaena odorata L. due to the presence of chemical compounds such as flavonoids, tannins, and saponins that have the potential as antibacterial. This study aims to determine the Minimum Inhibitory Concentration (MIC), and Minimum Bactericidal Concentration (MBC) ethanol extract of Chromolaena odorata L. leaves on the growth of Salmonella typhi and Staphylococcus aureus. This research is the initial stage of the development of herbal medicines to treat Salmonella typhi and Staphylococcus aureus infections. The study consisted of 5 treatments, namely concentrations of 20%, 40%, 60%, 80%, and 100% ethanol extract of Chromolaena odorata L. leaves with five repetitions. The antibacterial activity test was carried out by MIC and MBC methods. The research material uses leaves from Chromolaena odorata L. in the Sungai Besar area, Banjarbaru, South Kalimantan, Indonesia. The results showed that the average MIC yield of ethanol extract of Chromolaena odorata L. leaves against Salmonella typhi: 20% and Staphylococcus aureus: 20%. While the average yield of MBC values ​​against Salmonella typhi: 40% and Staphylococcus aureus: 40%. Based on the results obtained, it can be concluded that the ethanol extract of Chromolaena odorata L. leaves has an inhibitory effect on the growth of Salmonella typhi and Staphylococcus aureus. Chromolaena odorata L. leaves has potential as herbal medicine against bacterial infections but requires further research to determine its effect in vivo. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2020-09-17 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/104 10.33759/jrki.v2i3.104 Jurnal Riset Kefarmasian Indonesia; Vol. 2 No. 3 (2020): Jurnal Riset Kefarmasian Indonesia; 158-168 2655-8289 10.33759/jrki.v2i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/104/77 Copyright (c) 2020 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/105 2021-05-26T13:32:36Z jrki:ART driver

ANALISIS PEWARNA RHODAMIN B DAN PENGAWET NATRIUM BENZOAT PADA SAUS TOMAT YANG DIPERDAGANGKAN DI PASAR BESAR TRADISIONAL KOTA MALANG Jannah, Orchidosia Zukhruffin Suwita, Komang Jayadi, Lukky Saus Tomat, Rhodamin B, Natrium Benzoat One type of food product that usually uses food additives in the form of coloring agents and preservatives is sauce. Tomato sauce is a pasta-shaped product with a distinctive aroma of tomatoes. The number of sauces containing hazardous substances circulating in the community because of the increasing number of emerging home industries that do not use the correct rules for making sauces. The purpose of this study is to analyze the content of Rodhamin B coloring agents and levels of preservative Sodium Benzoate in tomato sauce traded in the Traditional Market of Malang City. The design of this study is observational, which is to dig data about the quality of tomato sauce in Malang City's Big Market by looking at the content of Rhodamin B Content and Sodium Benzoate. From the results of the study note that all tomato sauce samples do not contain Rodhamin B, while 2 of the 3 samples contain sodium benzoate preservative which exceeds the maximum threshold of 1gr / kg. Therefore, the public must be careful in buying tomato sauce products or other products that can be harmful to health. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2021-01-05 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/105 10.33759/jrki.v3i1.105 Jurnal Riset Kefarmasian Indonesia; Vol. 3 No. 1 (2021): Jurnal Riset Kefarmasian Indonesia; 10-17 2655-8289 10.33759/jrki.v3i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/105/82 Copyright (c) 2021 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/107 2020-09-24T08:29:47Z jrki:ART driver

GAMBARAN PENGETAHUAN MASYARAKAT DALAM PENGOBATAN SENDIRI (SWAMEDIKASI) UNTUK OBAT ANALGESIK Chusun, Chusun Lestari, Nanda Sinta Nyeri Self-medication is an alternative that is taken by the community to increase the affordability of treatment. This study aims to determine the description of Community Knowledge in Self-medication (Self-medication) for analgesics in Sukmajaya Village - Depok City. This research uses descriptive quantitative method. Samples were taken as many as 250 respondents from RW 09 and RW 10. Samples were taken randomly, the data obtained were analyzed univariate and bivariate with SPSS 20. The results showed that from 250 respondents, (90%) conducted self-medication with analgesic drugs, public knowledge. about high self-medication (72%) as well as knowledge of analgesics (58.8%). There is a significant relationship between education and self-medication, namely respondents who have low education have a chance of doing self-medication as well as knowledge of self-medication, namely respondents who have high self-medication knowledge have a chance of 3,193 times to do self-medication. The reason respondents did self-medication was because the disease was considered mild (52.4%). Source of drug information mostly comes from electronic media (88%). The analgesic drug that is widely used is paracetamol (63.6%). APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2020-09-24 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/107 10.33759/jrki.v2i3.107 Jurnal Riset Kefarmasian Indonesia; Vol. 2 No. 3 (2020): Jurnal Riset Kefarmasian Indonesia; 227-236 2655-8289 10.33759/jrki.v2i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/107/80 Copyright (c) 2020 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/108 2021-05-26T13:32:36Z jrki:ART driver

POTENSI INTERAKSI OBAT AMLODIPIN PADA PASIEN HIPERTENSI DISALAH SATU PUSKESMAS KABUPATEN SUMEDANG Anggriani, Ani Kusumahati, Eva Mutazam, Irfan Hilmi Interaksi Obat, Hipertensi, Amlodipin Hypertension is still a main health problem in indonesia, the purpose of this research is to know the profile of the antihypertensive agent and the interaction potency of the drugs and the relation between the amount of the drugs towards the interaction occurrence in public health centre of sukasari in district of sumedang by the period of July-December 2019. This was observational research with descriptive method. The data collection was performed using drug interaction checker software. There are data of 112 patients. The analysis was performed quantitatively and qualitatively. the result shows the interaction occurrence are happened to woman with percentage of 90% in age group of 65-74 years (30%). Hypertension stage 2 is the most occurred (69%), also there are 82 (73%) patients with potentially might have interaction, meanwhile from all medicines, there are 116 occurrence of interatction might happen. The most interaction occurred happen to amlodipin and hycrochlorothiazide (41%), with pharmacodynamic interaction of 62% and minor severity of 62%. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2021-01-05 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/108 10.33759/jrki.v3i1.108 Jurnal Riset Kefarmasian Indonesia; Vol. 3 No. 1 (2021): Jurnal Riset Kefarmasian Indonesia; 1-9 2655-8289 10.33759/jrki.v3i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/108/81 Copyright (c) 2021 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/110 2021-05-26T13:32:36Z jrki:ART driver

ANALISIS PENGGUNAAN ANTIBIOTIK PADA PASIEN ANAK DI RUANG THERESIA RUMAH SAKIT ST. ELISABETH SEMARANG DENGAN METODE ATC/DDD Rukminingsih, Fef Apriliyani, Apriliyani Antibiotic, ATC/DDD, DDD/100 patient-days, St. Elisabeth Hospital The high incidence of infectious diseases causes the use of antibiotics to increase. Inappropriate use of antibiotics will lead to resistance. Infectious diseases are included in the top 10 diseases in pediatric patients at St. Elisabeth Hospital.Semarang. This study aims to evaluate the use of antibiotics in pediatric patients in the Theresia ward of St. Elisabeth Hospital Semarang. This research is a descriptive observational study using retrospective data. Data were taken from medical records of pediatric patients in the Theresia ward at St. Elisabeth Hospital Semarang, aged 6 months - 14 years, the use of antibiotic therapy during the period October - December 2019. The data obtained were analyzed by calculating the quantity of antibiotic use using the Anatomical Therapeutic Chemical (ATC) and Defined Daily Dose (DDD)) / 100 patient-days methods. Based on the results of tracing medical record data, it was found that the number of pediatric patients in the Theresia room at St. Elisabeth Semarang for the period October - December 2019 is 385. The number of patients who received a single antibiotic was 162. The total value of DDD / 100 patient-days in the Theresia ward of St. Elisabeth Hospital Semarang for the period October - December 2019 is 18.17 with a total length of stay of 1117 days. The antibiotic with the highest DDD / 100 patient-days was ceftriaxone, namely 15.10. While the antibiotics that enter the DU 90% segment are ceftriaxone and cefotaxime. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2021-01-12 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/110 10.33759/jrki.v3i1.110 Jurnal Riset Kefarmasian Indonesia; Vol. 3 No. 1 (2021): Jurnal Riset Kefarmasian Indonesia; 26-34 2655-8289 10.33759/jrki.v3i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/110/84 Copyright (c) 2021 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/115 2021-05-26T13:32:36Z jrki:ART driver

FORMULASI DAN UJI DAYA HAMBAT SABUN CAIR EKSTRAK ETANOL SERAI WANGI (Cymbopogon nardus L) TERHADAP PERTUMBUHAN Staplylococcus aureus Rinaldi, Rinaldi Fauziah, Fauziah Mastura, Rizka sabun cair, Formulasi, daya hambat, Staphylococus aureus Citronella (Cymbopogon Nardus.L) contains essential oil compounds, saponins, polyphenols and flavonoids which are antibacterial. The use of active compounds of Citronella is formulated into antibacterial liquid soap preparations. This study aims to determine the characteristics of liquid soap and its inhibition against the growth of Staphylococcus aureus. This research is experimental to formulate liquid soap containing ethanol extract of lemongrass sticks at concentrations of 9% (F1), 18% (F2) and 24% (F3). The test parameters for liquid soap preparations include organoleptic test (shape, aroma, color), homogeneity test, pH test, foam height test, foam stability test, free alkaline test and inhibition test against the growth of Staphylococcus aureus using the Kirby-Bauer method. The results showed that the liquid soap preparations in the F1, F2 and F3 formulas were liquid, had a distinctive aroma of Citronella and were brown in color, homogeneous. The pH values, foam height, foam stability and free alkaline content of liquid soap were F1 (12; 70 mm; 85.7% and 0.14%), F2 (11. 80 mm, 87.5% and respectively). 0.10%), F3 (10.100 mm, 90% and 0.08%). The formula inhibition zone diameters are 32.06 mm, 25.6 mm and 29.2 mm, respectively. The conclution is the characteristics of the liquid soap with the ethanol extract of Citronella (Cymbopogon Nardus.L) meet the requirements as liquid soap. The greatest inhibitory effectiveness on the growth of Staphylococcus aureus was a formula at a concentration of 24% (F3) with a strong category.  APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2021-01-16 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/115 10.33759/jrki.v3i1.115 Jurnal Riset Kefarmasian Indonesia; Vol. 3 No. 1 (2021): Jurnal Riset Kefarmasian Indonesia; 45-57 2655-8289 10.33759/jrki.v3i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/115/86 Copyright (c) 2021 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/117 2021-05-26T13:32:36Z jrki:ART driver

POLA PERESEPAN ANTIBIOTIK PROFILAKSIS PRE BEDAH SECTIO CAESAREA DI RUMAH SAKIT Saleh, Chusun Kurniasari, Maya Antibiotik Profilaksis Sectio Caesarea Caesarean section is a surgery to give birth to a child through surgery on the abdominal wall and uterus. Prophylactic antibiotics are preventive antibiotics in Sectio Caesarean surgery.     This study aims to determine the pattern of prescribing prophylactic antibiotics in preoperative caesarean section patients which are grouped into 4 specific objectives, namely: patient characteristics such as (age, parity status, payment status), antibiotic class, type of antibiotic, and to determine surgical wound indication ILO, This study used a descriptive method by retrospectively taking data by looking at the prescription (e-prescription), patient medical record data and SOAP (Subjective, Objective, Assessment, Planning). The results showed that out of 300 patients who were parturient, 52 patients (17.3%) had normal delivery and 248 patients with caesarean delivery (82.7%). Most of the ages were between 20-30 years as many as 123 patients (49.6%) and aged > 30-40 years as many as 120 patients (48.38%). As for the status of the most payments in cash, namely 176 patients (71%). The most frequently used antibiotic class is the Cephalosporin group, namely 246 patients (99.6%), the most commonly used type of antibiotic is Ceftriaxon, which is 175 patients (70.6%). The study on Surgical Wound Infection was found in only 1 patient (0,4%) with the antibiotic Ceftriaxon. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2021-01-22 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/117 10.33759/jrki.v3i1.117 Jurnal Riset Kefarmasian Indonesia; Vol. 3 No. 1 (2021): Jurnal Riset Kefarmasian Indonesia; 65-76 2655-8289 10.33759/jrki.v3i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/117/92 Copyright (c) 2021 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/118 2021-05-26T13:32:36Z jrki:ART driver

UJI KANDUNGAN TIMBAL (Pb) PADA GORENGAN YANG DIJUAL DI PINGGIR JALAN SEPANJANG PANTAI GANDORIAH PARIAMAN SECARA SPEKTROFOTOMETRI SERAPAN ATOM Yulia, Mega Syahrianti, Dani Yulis, Rahma Timbal Gorengan Spektrofotometri serapan atom             Lead is one of the heavy metal elements found in the air pollution which is produced together with motor vehicle fumes. Lead can cause various disorders in human body such as anemia, neurological damage, deformities and body functions, dental caries, impaired kidney function, effects on the heart and infertility. Lead can enter the human body through inhaled air, through the skin and ingested with food. The purpose of this study was to determine the lead content in fried foods (fried sala, fried crab, fried shrimp and fried fish) sale around of Gandoriah Beach, Pariaman. This research was conducted at Baristand Laboratory (Research and Standarirdization Industry Center) Padang from February until March 2020. This study was conducted on 4 samples taken randomly from the total population. The instrument used was atomic absorption spectrophotometry (AAS). The results of 4 samples showed that the lead content in fried sala was 0.1618 mg/kg, with a maximum SNI limit is 0.3 mg/kg, fried crab was 0.4025 mg/kg with a maximum SNI limit is 0,5 mg/kg, fried shrimp was 0.4377 mg/kg with a maximum SNI limit is 0.5 mg/kg, fried fish was 0.2331 mg/kg with an SNI maximum limit is 0.3 mg/kg. Based on the results of this study, it can be concluded all samples contain lead but the level is still below of maximum limit of SNI 7387-2009. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2021-01-09 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/118 10.33759/jrki.v3i1.118 Jurnal Riset Kefarmasian Indonesia; Vol. 3 No. 1 (2021): Jurnal Riset Kefarmasian Indonesia; 18-25 2655-8289 10.33759/jrki.v3i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/118/83 Copyright (c) 2021 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/124 2021-05-31T14:17:57Z jrki:ART driver

OPTIMASI CAMPURAN AVICEL PH 101 DAN LAKTOSA SEBAGAI BAHAN PENGISI PADA TABLET EKSTRAK BUNGA ROSELLA (Hibiscus sabdariffa L.) SECARA GRANULASI BASAH Kokafrinsia, Zila Tjhia Saryanti, Dwi Formula optimal Simplex Lattice Design Kerapuhan Rosella flower (Hibiscuss sabdariffa L.) in traditional medicine can provide protection against various diseases, such as coronary heart disease, cancer, lowering cholesterol, and liver disorders. This study aims to obtain the optimum formula of tablet of rosella flower extract with a mixture of Avicel PH 101 and lactose as a filler using wet granulation method. Rosella flower extract was obtained by maceration of rosella flower powder using 70% ethanol. The optimization formula for tablets using the Simplex Lattice Design method with Design Expert software version 10. The parameters used in the optimization are weight variation, hardness, friability and disintegration time. Verification of the optimal formula using the SPSS 18 program with the One Sample T-test method with a confidence level of 95%. The results showed that the optimal formula of tablet of rosella flower extract was the Avicel PH 101 97.82%: 2.17% lactose. The optimal formula has weight variation 1.53% ± 0.0073; hardness 5.087 kg ± 0.5135; the friability is 0.3% ± 0.041. The resulting disintegration was 22.99 minutes ± 2.218. The results of the verification of the optimal formula show that there is no significant difference between the predictions of the Simplex Lattice Design method and the results of the tests performed so that it can be said that the method is valid. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2021-05-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/124 10.33759/jrki.v3i2.124 Jurnal Riset Kefarmasian Indonesia; Vol. 3 No. 2 (2021): Jurnal Riset Kefarmasian Indonesia; 102-116 2655-8289 10.33759/jrki.v3i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/124/101 Copyright (c) 2021 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/125 2021-05-26T13:32:36Z jrki:ART driver

IDENTIFIKASI BORAKS PADA PENTOL BAKSO YANG DI KELURAHAN AIR HITAM DENGAN PEREAKSI KULIT BUAH NAGA MERAH (Hylocereus polyhizus) Lestari, Dwi Dewi, Mutia Ningsih, Suci Cahya Hidayati, Hidayati Pentol Bakso Boraks Borax is often misused to preserve various foods such as wet noodles, meatballs, rice cake, rhombus and so on. Red dragon fruit skin contains secondary metabolites, namely anthocyanin, anthocyanin is the most important and widespread dye in the skin of red dragon fruit, but the use of red dragon fruit peels has not been studied much naturally. The purpose of this study was to identify borax on the meatball sold in the Air Hitam district with the red dragon fruit skin reagent (Hylocereus polyhizus). This research is experimental with data collection techniques by accidental sampling. In this study used several samples of meatball pentol purchased at the meatball merchant located in Air Hitam Village by using dragon fruit peel and AgNO3 reagent as a comparison indicator. This research includes plant determination, sample collection, sample preparation, spike making, dragon fruit skin extract reagents and qualitative sample testing. Data analysis using descriptive analysis method. The results of the identification of borax on 5 meatball samples using color reagents from the extract (essence) of the red dragon fruit peel and AgNO3 reagent as a comparative indicator showed that all samples of the meatball obtained Negative results APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2021-01-17 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/125 10.33759/jrki.v3i1.125 Jurnal Riset Kefarmasian Indonesia; Vol. 3 No. 1 (2021): Jurnal Riset Kefarmasian Indonesia; 58-64 2655-8289 10.33759/jrki.v3i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/125/88 Copyright (c) 2021 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/129 2021-05-31T13:53:12Z jrki:ART driver

UJI IN VIVO TAHAP PREKLINIS TERHADAP EKSTRAK BATANG PISANG (Musa paradisiaca L.) SEBAGAI ANTIINFLAMASI TOPIKAL Dewi, Ni Luh Kade Arman Anita Yuda, Putu Era Sandhi Kusuma Suarnata, I Gede Agus Sasadara, Maria Malida Vernandes Ekstrak Batang pisang Karagenan 1% Inflammation is a normal protective response to tissue injury caused by physical trauma, chemical damage, or microbiological substances. Banana stems (Musa paradisiaca L.) have been empirically believed for their topical anti-inflammatory properties. The purpose of this study was to scientifically evaluate the in vivo preclinical anti-inflammatory activity of banana stems. This research was designed experimentally using twenty-five albino male rats which were divided into five groups: the positive control group which received sodium diclofenac gel, the negative control group which received gel basis preparation without any active ingredient, and three experimental groups which received banana stem extract gel in three different concentrations, 5%, 10%, and 15%. Every five rats of every group were firstly injected with 1% of carrageenan, and the anti-inflammatory effect was evaluated every hour for 4 hours using a plethysmometer.  The collected data were statistically evaluated. The results showed that banana stem extract gel with concentrations of 15% produced the best anti-inflammatory effect, compared to other gel concentrations. In conclusion, the preparation of 15% banana stem extract gel can be applied as potential topical anti-inflammatory preparation. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2021-05-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/129 10.33759/jrki.v3i2.129 Jurnal Riset Kefarmasian Indonesia; Vol. 3 No. 2 (2021): Jurnal Riset Kefarmasian Indonesia; 138-151 2655-8289 10.33759/jrki.v3i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/129/104 Copyright (c) 2021 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/131 2021-05-31T13:53:12Z jrki:ART driver

ISOLASI SENYAWA AKTIF DAN UJI AKTIVITAS EKSTRAK JAHE MERAH (ZINGIBER OFFICINALE) SEBAGAI IMUNOMODULATOR Masniah, Masniah Rezi, Jafril Faisal, Ahmad Purnawarman Jahe Zingiber officinale Imunostimulator Red ginger (Zingiber officinale) contains many chemical compounds that have many activities. This study aims to determine the active compounds of Zingiber officinale and immunomodulatory activity that can increase the phagocytosis of macrophage cells and lymphocyte cell proliferation. Red ginger extract compounds were identified using GC-MS. The parameters of immunostimulatory activity were macrophage phagocytosis and lymphocyte proliferation, the preparations were made in several extract concentrations. This research is an experimental study in the laboratory. The research included fresh red ginger, made into ethanol extract, dried. The results were made a suspension, the extract was then given to macrophage cells (phagocytosis testing) and lymphocyte cells (proliferation testing) in vitro to test the immunomodulatory effect. The results showed that the most active extract in macrophage phagocytosis activity was the extract concentration of 500 ppm. While the activity of lymphocyte proliferation was shown by the concentration of group A (Cell, 500 ppm extract, MK, Engerik). The active compound contained in the ethanol extract of red ginger is thought to be Geraniol APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2021-05-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/131 10.33759/jrki.v3i2.131 Jurnal Riset Kefarmasian Indonesia; Vol. 3 No. 2 (2021): Jurnal Riset Kefarmasian Indonesia; 77-91 2655-8289 10.33759/jrki.v3i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/131/105 Copyright (c) 2021 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/134 2021-05-31T13:53:12Z jrki:ART driver

PENGENDALIAN PENGELOLAAN OBAT DI INSTALASI FARMASI SUATU RUMAH SAKIT SWASTA KOTA BANDUNG Lisni, Ida Samosir, Herman Mandalas, Ester Evaluasi Pengelolaan Obat Instalasi Drug management is a series of planning, procurement, storage, distribution, and control activities carried out by a hospital pharmacy so that drug availability can be guaranteed in sufficient quantities, in its implementation requires a large number of funds. The study was conducted to evaluate drug management in private hospital pharmacies in the city of Bandung using predetermined standard indicators. This study used a retrospective non-experimental observational method. The data collected is in the form of planning data and drug procurement, drug use, drug stock cards, stock-taking reports. The results showed that the achievement of drug planning (107.53%), the frequency of purchase for the low category (34.70%), the medium category was 41.08% and the high category (24.22%), expired drugs (0.085%) and the dead stock (3.81%). APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2021-05-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/134 10.33759/jrki.v3i2.134 Jurnal Riset Kefarmasian Indonesia; Vol. 3 No. 2 (2021): Jurnal Riset Kefarmasian Indonesia; 92-101 2655-8289 10.33759/jrki.v3i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/134/100 Copyright (c) 2021 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/135 2021-05-31T23:51:14Z jrki:ART driver

PENGARUH KOMUNIKASI TENAGA FARMASI DALAM UPAYA PENINGKATAN PEMAHAMAN LANSIA TERHADAP DAGUSIBU OBAT (DAPATKAN, GUNAKAN, SIMPAN, BUANG) DI DESA KOPEN KABUPATEN BOYOLALI Anisawati, Amanda Isma, Faizatul Tansa, Ilham La Hanifah, Rafidah Diana, Rizky Nur Santoso, Aris Prio Agus Komunikasi Tenaga Farmasi Dagusibu Irrational use of drugs and their abusers is a problem that is often found in society.  Based on the survey data obtained, there are still residents who get drugs freely without monitoring medical and pharmaceutical personnel or the drugs purchased are medicines from grocery stores, and many residents in Kopen village, Boyolali, do not know how to use appropriate drugs and how to store them.  The correct medicine and many of them are still throwing away liquid medicine in the package and without paying attention to damage the medicine package. Education about the drug Dagusibu is one of the efforts we do as pharmaceutical personnel to prevent irrational drug use and to prevent drug abuse by the community, especially the elderly in Kopen Village, Boyolali.  The method used is a preventive intervention method and a quantitative approach to the elderly using the Dagusibu questionnaire that we created.  Based on filling out the questionnaire before we do the socilization, it was found that 73% of the elderly who do not understand, 18% of the elderly who have little understanding and 7% of the elderly who are accompanied by a guardian who already understands. The understanding of Dagusibu drugs by the elderly in the Village Kopen, Boyolali categorized't get it. It needs to be held socialization to improve the understanding of the elderly and also residents in the Village kopen, Boyolali. After socialization, the obtained results of the questionnaire 27% still do not understand, 64% already understand and also 9% are elderly, accompanied by a guardian in the use of the drug. The conclusion of this research is the role of pharmaceutical personnel hold a very important role in conveying information and education in an improved understanding of the elderly and residents in the Village kopen, Boyolali.. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2021-05-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/135 10.33759/jrki.v3i2.135 Jurnal Riset Kefarmasian Indonesia; Vol. 3 No. 2 (2021): Jurnal Riset Kefarmasian Indonesia; 126-137 2655-8289 10.33759/jrki.v3i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/135/103 Copyright (c) 2021 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/137 2021-10-01T02:00:56Z jrki:ART driver

GAMBARAN PENGGUNAAN TERAPI GEA (GASTROENTERITIS ) PADA PASIEN ANAK DI RSUD BATARA SIANG PANGKEP SULSEL Wahyuni, Dwi Fitrah Riska, Riska Diarrhea Therapy Patient GEA (Gastroenteritis) or diarrhea is a disease caused by digestive tract disorders that are infected by bacteria. Treatment of early diarrhea, especially the choice of initial therapy, greatly affects the success of providing appropriate and appropriate therapy. This study aims to determine the rationality of therapy in pediatric patients at Batara Siang Pangkep Regional Hospital, South Sulawesi City. This study is a non-experimental study with a retrospective descriptive evaluation study using patient medical records. The samples that met the inclusion criteria were 65 patients. Acute diarrhea was mostly found in men as many as 38 patients (58%) while for women as many as 27 patients (42%). Characteristics of age 1-3 years (82%). The result showed that there are 3 therapeutic regimen in pediatric patient namely cotrimoxazole,electrolit, and zinc. So from these data meet the standards of management of diarrheal disease in children. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2021-09-29 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/137 10.33759/jrki.v3i3.137 Jurnal Riset Kefarmasian Indonesia; Vol. 3 No. 3 (2021): Jurnal Riset Kefarmasin Indonesia; 189-198 2655-8289 10.33759/jrki.v3i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/137/117 Copyright (c) 2021 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/140 2021-05-31T13:53:12Z jrki:ART driver

GAMBARAN PERSEDIAAN OBAT DI APOTEK NIAS MEDIKA DENGAN ANALISIS ABC BERDASARKAN RESEP MASUK PERIODE JANUARI-MEI 2020 Nofrika, Vonny Agustina, Ika Priyanti, Risca Apotek Manajemen Analisis ABC Pharmacy is a pharmaceutical service facility where pharmacy practices are carried out by pharmacists, namely manufacturing including quality control of pharmaceutical preparations, security, procurement, storage and distribution or distribution of drugs, drug management, prescription drug services, drug information services, and drug development services, drug ingredients and traditional medicine One of the scopes in the management of health services is logistics management, which is a field of management whose specific task is to deal with logistics. Pharmacy nias medika there was no specific arrangement for the procurement of drugs with certain methods so that often there is a vacuum of medicine one of which is for drugs contained in a doctor's prescription that goes to the nias medika pharmacy. For this reason, it was necessary to control drug inventory using certain methods, one of which was by using ABC analysis. The type of research was descriptive and quantitative, based on the prescription entry by recording the name of the drug, the number of drugs, and the unit price of the drug and then processed using data analysis during January-May 2020. The results showed that there were 160 types of drugs based on prescription entry into the drugstore nias medika. With 32 types (20% ) drugs classified as group A with an investment value of 69.68% with laroton drugs which are in the highest position 47 types (29.37%) drugs classified as group B with an investment value of 20.25%, while 81 types (50, 63%) the drugs belong to group C with a total investment of 10.07%. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2021-05-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/140 10.33759/jrki.v3i2.140 Jurnal Riset Kefarmasian Indonesia; Vol. 3 No. 2 (2021): Jurnal Riset Kefarmasian Indonesia; 117-125 2655-8289 10.33759/jrki.v3i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/140/102 Copyright (c) 2021 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/156 2021-10-01T02:00:56Z jrki:ART driver

PENGARUH TERAPI FARMAKOLOGI DAN NON-FARMAKOLOGI TERHADAP PENURUNAN NYERI MENSTRUASI PADA MAHASISWI FAKULTAS FARMASI UNIVERSITAS BHAKTI KENCANA BANDUNG Anggriani, Ani Mulyani, Yani Pratiwi, Lili Dinda Pharmacology Non-Pharmacology Menstrual pain Menstrual pain is a problem that women often complain about in their teens. Menstrual pain (dysmenorrhea) is pain before or during menstruation in the lower abdomen due to uterine cramps. The prevalence of dysmenorrhea in Indonesia is 54% primary dysmenorrhea and 9% secondary dysmenorrhea. Due to the severe pain that is felt during menstruation, 10% of teenage girls are absent from school and work for 3 days each month. This study aims to determine the effect of pharmacological & non-pharmacological therapy on reducing menstrual pain in adolescents. This research is an experimental research with one group pretest-post test design. The research sample used purposive sampling method, with a sample of 76 respondents. Data were analyzed using the Wilcoxon Signed Rank Test & chi-square test. The results showed that the Wilcoxon test with the results of Sig. 0.000<0.05, meaning that there is a difference in the intensity of menstrual pain before & after therapy. So it can be concluded that there is an effect of pharmacological and non-pharmacological therapy on decreasing the intensity of menstrual pain. For the relationship of non-pharmacological therapy Chi-Square test results have a value of Sig. 0.514>0.05, meaning that there is no significant relationship to the intensity of menstrual pain. For the relationship between pharmacological therapy, the results of Sig. 0.019<0.05, meaning that there is a significant relationship with the intensity of menstrual pain in adolescent girls at Bhakti Kencana University, Bandung. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2021-09-29 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/156 10.33759/jrki.v3i3.156 Jurnal Riset Kefarmasian Indonesia; Vol. 3 No. 3 (2021): Jurnal Riset Kefarmasin Indonesia; 174-188 2655-8289 10.33759/jrki.v3i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/156/116 Copyright (c) 2021 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/167 2021-10-01T12:54:28Z jrki:ART driver

PENGARUH PENAMBAHAN POLIETILEN GLIKOL 6000 PADA TABLET IBUPROFEN DISPERSI PADAT TERHADAP ABSORBSI IBUPROFEN SECARA IN SITU Tampubolon, Antetti solid dispersion ibuprofen PEG6000 in situ Drug absorption can be decided by various methods, namely in vitro methods, in situ methods, and in vivo methods. The in situ method is a procedure that is very close to the in vivo method. The aim of this study was to identify the effect of accumulation of polyethylene glycol 6000 (PEG 6000) on solid dispersion of ibuprofen tablets on the in-situ absorption of the drug. This research was conducted through an experiment to determine the effect of adding polyethylene glycol 6000 to the absorption of ibuprofen in situ by flowing the solution from solid dispersion ibuprofen tablets, solutions from generic ibuprofen tablets and standard ibuprofen solutions. The solid dispersion system was carried out by melting ibuprofen and polyethylene glycol 6000 in a ratio of 1:05. The drug solution was flowed through the lumen of the small intestine of male rats. Unabsorbed ibuprofen was measured by an ultraviolet spectrophotometer at a wavelength of 225.5 nm. Next, the absorbed level of ibuprofen was calculated. The results showed that ibuprofen from solid dispersion tablets was absorbed more than ibuprofen from generic tablets and standard ibuprofen. It can be concluded that polyethylene glycol 6000 has an effect on the absorption of ibuprofen in situ. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2021-09-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/167 10.33759/jrki.v3i3.167 Jurnal Riset Kefarmasian Indonesia; Vol. 3 No. 3 (2021): Jurnal Riset Kefarmasin Indonesia; 211-222 2655-8289 10.33759/jrki.v3i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/167/119 Copyright (c) 2021 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/169 2021-10-01T02:00:56Z jrki:ART driver

UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN MANGGA KASTURI (Mangifera casturi Kosterm.) Lestari, Dwi MA, Muthia Dwi Pratiwi, Jati Saputri, Lidya Handoko Mangifera casturi Kosterm Leaf DPPH Mangga Kasturi (Mangifera casturi Kosterm.) is one of the plants in Indonesia that has potential as an antioxidant. The purpose of this study was to determine the IC50 value and antioxidant potential of the ethanol extract of mangga kasturi leaves (Mangifera casturi Kosterm.). The ethanol extract of mangga kasturi leaves (Mangifera casturi Kosterm.) was extracted using maceration with 96% ethanol as solvent. The antioxidant activity test was carried out using the DPPH (1,1-Diphenyl-2-Picrylhydrazil) method using a UV-Vis spectrophotometer and vitamin C as a comparison. The results of phytochemical screening tests on ethanol extracts showed positive secondary metabolites such as alkaloids, flavonoids, tannins, and quinones. Testing the ethanol extract of Mangga Kasturi leaves (Mangifera casturi Kosterm.) with the DPPH method showed that the ethanol extract had an antioxidant activity with an IC50 value of 83.61 ppm in the strong category of antioxidant potential. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2021-09-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/169 10.33759/jrki.v3i3.169 Jurnal Riset Kefarmasian Indonesia; Vol. 3 No. 3 (2021): Jurnal Riset Kefarmasin Indonesia; 162-173 2655-8289 10.33759/jrki.v3i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/169/115 Copyright (c) 2021 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/179 2021-10-01T02:00:56Z jrki:ART driver

LAJU FILTRASI GLOMERULUS PASIEN DIABETES MELITUS TIPE II DI SALAH SATU RUMAH SAKIT SWASTA DI KABUPATEN DEMAK Rukminingsih, Fef Widiastuti, Mei Glomerulus Filtration Rate JKN Participants DM Type II Diabetes Mellitus (DM) Type II is a group of metabolic diseases with hyperglycemia characteristics. The use of oral hypoglycemic drugs (OHO) lasts for a relatively long time. Most of the OHO is excreted through the kidneys. This study aims to determine the Glomerulus Filtration Rate (GFR) of type 2 DM patients who use OHO at the "X" Hospital, District of Demak. This study is an observational descriptive study using retrospective data obtained from medical record data (RM) of outpatient JKN participants with type 2 DM for the period October-December 2020. Inclusion criteria were patients who received OHO for at least one year with or without comorbidities, aged 36-65 years, and had a serum creatinine test. Patients receiving combination therapy with insulin were excluded. LFG is calculated using the Cockroft-Gault formula. From 82 patients, 52 patients (62.2%) were female, 74 patients (90.2%) were more than 45 years old. Patients who consumed OHO for more than 2 years were 47 (57.3%). Patients without comorbidities were 62 (75.7%) people. Patients who experienced a decrease in GFR in the moderate category (stage 3) as many as 24 people (29.3%), a decrease in GFR in the severe category (stage 4) as many as 5 people (6.1%) and 1 person (1.2%) experienced End Stage Renal Disease. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2021-09-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/179 10.33759/jrki.v3i3.179 Jurnal Riset Kefarmasian Indonesia; Vol. 3 No. 3 (2021): Jurnal Riset Kefarmasin Indonesia; 152-161 2655-8289 10.33759/jrki.v3i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/179/114 Copyright (c) 2021 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/184 2021-10-01T02:00:56Z jrki:ART driver

ANALISIS KANDUNGAN PEMANIS BUATAN SIKLAMAT PADA SIRUP YANG BEREDAR DIPASAR BESAR MALANG SECARA KUANTITATIF MENGGUNAKAN METODE SPEKTROFOTOMETRI UV-VIS Jayadi, Lukky Hernaningsih, Maritha Syrup Sodium Cyclamate UV-Vis Spectrophotometry Sweeteners are chemical compounds that are often added and used for industrial food processing products as well as beverages and foods, sweeteners consist of natural sweeteners and synthetic sweeteners, one of the synthetic sweeteners is sodium cyclamate. This study aims to identify and determine the level of sodium cyclamate in syrup by UV spectrophotometry method and to determine the level of sodium cyclamate in syrup is still safe for consumption. The type of research is experimental and descriptive. The research sample used is syrup which is sold in the big market of Malang City. The method used for the determination of sodium cyclamate levels was done by UV spectrophotometry whose absorption was measured at a maximum wavelength of 314 nm. The results of the quantitative analysis showed that there were positive samples containing sodium cyclamate, namely sample 1, sample 2 and sample 3. The assay results in sample 1 were 238.78 mg/kg, sample 2 was 239.65 mg/kg and sample 3 was 241.39 mg/kg. Of the three samples tested for levels of cyclamate in syrup sold in the big market in Malang City, they still meet the requirements set by the head of the Food and Drug Supervisory Agency. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2021-09-29 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/184 10.33759/jrki.v3i3.184 Jurnal Riset Kefarmasian Indonesia; Vol. 3 No. 3 (2021): Jurnal Riset Kefarmasin Indonesia; 199-210 2655-8289 10.33759/jrki.v3i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/184/118 Copyright (c) 2021 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/200 2022-01-28T23:42:03Z jrki:ART driver

AKTIVITAS ANTIOKSIDAN DARI DAUN BINTANGUR (Calophyllum inophyllum L.) TERHADAP RADIKAL BEBAS DPPH (1,1 Difenil-2-pikrihidrazil Faisal, Ahmad Purnawarman Nasution, Pratiwi Rukmana Wakidi, Riza Fahlevi Antioksidan DPPH Bintangur Calophyllum inophyllum L. Antioxidants are compounds that can inhibit oxidation reactions by binding to free radicals and highly reactive molecules. Bintangur contains saponins, tannins, flavonoids and alkaloids. In the presence of flavonoids, the purpose of this study is to understand the antioxidant activity of ethanol extracts against DPPH free radicals, and the IC50 parameter has the highest antioxidant activity. Use ethanol to macerate Bintangur leaf powder. Analyze the content of secondary metabolites in ethanol extracts. Use a spectrophotometer to test the antioxidant activity of the obtained extract against DPPH free radicals at a wavelength of 517 nm, and determine the IC50 value. Routine was used as a positive control in this study. The results of three repeated studies showed that the IC50 values ​​of the ethanol extract were 65.49 ppm, 65.76 ppm, and 65.76 ppm, respectively. Average IC50 value is 55.67 ppm. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/200 10.33759/jrki.v4i1.200 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 1 (2022): Jurnal Riset Kefarmasian Indonesia; 1-10 2655-8289 10.33759/jrki.v4i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/200/128 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/208 2022-01-28T23:42:03Z jrki:ART driver

IDENTIFIKASI PARASETAMOL DALAM JAMU PEGAL LINU YANG DIPEROLEH DARI DEPOT JAMU DI KOTA DENPASAR Ni Made, Maharia Ningsih Identification Paracetamol Herbal pain relief The use of traditional medicine in the form of herbal medicine is in great demand by the people of Indonesia, one of that is pegal linu herb. Based on PERMENKES No. 006/Menkes/Per/V/2012 articles 33 and 37 states that traditional medicine may not contain medicinal chemical. Medicinal chemical that is often added into herbal medicine for pegal linu herb is paracetamol.This study aims to determine the presence of paracetamol in pegal linu herb depots in Denpasar city. The research method used an exploratory descriptive method and samples of herbal medicine were taken by purposive sampling, 14 samples of herbal medicine of various brands that was sold at depots in Denpasar City. The research was conducted at the chemical laboratory of Bali International University in July 2021. After preparation, the fourteen samples of herbal medicine were identified using Thin Layer Chromatography (TLC) with selection mobile phase ethanol p.a, detection with UV light 254 nm and 0.05 M H2SO4 sprayer. Completeness identification was also carried out descriptive labeling of herbal products containing paracetamol. Positive samples contain paracetamol if the Rf value and spot color are similar to the paracetamol comparison standard. The Rf results obtained that samples with codes F, I, K, and L were 0.68; 0.68; 0.68 and 0.68 which are the similar as the standard Rf for comparison of paracetamol and positive control which is 0.69. The conclusion of the research is that there are various brands of pegal linu herb sold in Indonesia that are suspected to contain 4 brands of paracetamol. Research suggestions for consumers who consume a brand of traditional herbal medicine are expected to be more selective in choosing herbal medicine by first checking the product registration number. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-01-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/208 10.33759/jrki.v4i1.208 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 1 (2022): Jurnal Riset Kefarmasian Indonesia; 74-88 2655-8289 10.33759/jrki.v4i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/208/136 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/212 2022-01-28T23:42:03Z jrki:ART driver

FORMULASI HARD CANDY DARI SARI BUAH JERUK NIPIS (Citrus aurantifolio), MADU (Mell depuratum) DAN KAYU MANIS (Cinnamomum burmanii) BERDASARKAN PERBEDAAN SIRUP GLUKOSA Yulia, Mega Azra, Fadhilla Putri Ranova, Riki hard candy Formulation Lime Honey Lime is a fruit that is widely used by people for treatment cough. For efficiency use of lime, it can processing to product that easier for using such as hard candy. This study aims to determine the results of physical tests and panelists preference for hard candies made from lime juice, honey and cinnamon. The method used is an experimental method by combining lime juice, honey, cinnamon and varying glucose syrup as a candy forming ingredient. Physical evaluation of each formula which includes analysis of water content and ash content, also hedonic test of 3 formulas to 100 panelists. The results of the physical evaluation carried out on the 3 formulas showed that all formulas met the quality requirements of SNI 3547.1:2008 hard candy for water content and ash content, also the results of the hedonic test using non parametric SPSS showed that there was a significant effect on taste and texture where formula III was the most preferred by panelist. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-01-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/212 10.33759/jrki.v4i1.212 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 1 (2022): Jurnal Riset Kefarmasian Indonesia; 89-100 2655-8289 10.33759/jrki.v4i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/212/137 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/214 2022-01-28T23:42:03Z jrki:ART driver

PERSEPSI MAHASISWA DALAM PEMBELAJARAN DARING PADA MATA KULIAH FARMASI SIMULASI DI MASA PANDEMI COVID-19 Maryanti, Lilis Rulianti, Mona Rahmi Yuliani, Yuliani Online Learning Student’s Perception This study aims to determine student perceptions of online learning in simulated pharmacy courses during the Covid-19 pandemic. This type of research is descriptive research. Sampling used a purposive sampling technique with clear inclusion criteria, namely students who had received a simulated pharmacy practice course in the fifth semester of the Pharmacy Department of the Health Polytechnic of the Ministry of Health of Palembang as many as 77 students. Questionnaires distributed via google form with a Likert-scale and one essay question. Analysis of the data is used by calculating the percentage of respondents and analyzing each indicator. The research results obtained are good perceptions from students of online learning in simulated pharmacy courses during the Covid-19 pandemic. The score for the percentage of respondents obtained for the teaching and learning process indicators shows good criteria of 72.7%, for lecturers' competence indicators showed good criteria of 79.2%, while for facilities and infrastructure indicators also showed good criteria of 75.1% APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-01-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/214 10.33759/jrki.v4i1.214 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 1 (2022): Jurnal Riset Kefarmasian Indonesia; 46-58 2655-8289 10.33759/jrki.v4i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/214/134 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/218 2022-01-30T13:02:56Z jrki:ART driver

EVALUASI SEDIAAN MASKER GEL PEEL-OFF KOMBINASI EKSTRAK DAUN MANGGA BACANG (Mangifera foetida)DAN DAUN SALAM (Syzygium polyanthum) Putriani, Kony Mardhiyani, Dini Anggraini, Lovera Peel-off gel mask evaluation Mangifera foetida Syzygium polyanthum Mango Bacang leaves and bay leaves are plants that can be used as ingredients in traditional medicine as natural antibacterials which are believed to help get rid of acne.  Several previous studies also reported that Bacang mango leaves and bay leaves have activity against Staphylococcus aureus, Escherichia coli and Salmonella typhi bacteria.  This study aims to determine the evaluation results of peel-off gel mask preparations that meet the requirements.  The test methods include organoleptic test, pH test, viscosity, homogeneity test and dispersion test.  The test results showed that F1 and F2 were the best formulas with the characteristics of a green-black gel, a characteristic odor of mango Bacang and bay leaves, a viscosity of 1129 cPs and 1135 cPs, pH 4.4 and 4.5.  The dispersion test was 5.1 cm and 5.7 cm and the homogeneity test on the peel off gel mask was homogeneous, there were no fibers, lumps or differences in color when applied to a transparent slide. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-01-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/218 10.33759/jrki.v4i1.218 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 1 (2022): Jurnal Riset Kefarmasian Indonesia; 111-123 2655-8289 10.33759/jrki.v4i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/218/139 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/219 2022-01-30T12:42:22Z jrki:ART driver

FORMULASI EKSTRAK ETANOL DAUN ALPUKAT (Persea americana Mill) DAN DAUN SIRIH (Piper betle) SEBAGAI REPELLANT (ANTI NYAMUK) BERBENTUK MAT ELEKTRIK TERHADAP NYAMUK Aedes aegypti Yunus, Arifuddin Wahyuni, Dwi Fitrah Nurzak, An Nisaa Dengue Fever Avocado Leaf Betel Leaf Repellant Aedes aegypti The epidemiology and area of the spread of DHF is increasing along with the increasing mobility and population density. One of the efforts made in eradicating mosquito vectors is by using insecticides. This study aimed to examine the effectiveness of the combination of avocado (Persea americana) and betel leaf (Piper betle) ethanol extracts against the death of Aedes aegypti mosquitoes. This study aimed to examine the effectiveness of the combination of avocado (Persea americana) and betel leaf (Piper betle) ethanol extracts against the death of Aedes aegypti mosquitoes. This research design is experimental with post test only control group design. The electric mat that had been soaked with a combination of ethanolic extract of avocado (Persea americana) and ethanolic extract of betel leaf (Piper betle) was divided into 4 concentration groups, namely positive control, negative control, and a combination of extracts with concentrations of 1%, 3% and 5 %. Then tested with 10 Aedes aegypti mosquitoes in each treatment. Then tested with 10 Aedes aegypti mosquitoes in each treatment. The results showed that at a concentration of 5% it was able to kill 10 Aedes aegypti mosquitoes in just 5 minutes compared to concentrations of 1% and 3%. From this study it can be concluded that the greater the concentration of extract used, the faster the duration of time to kill the Aedes aegypti mosquito. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-01-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/219 10.33759/jrki.v4i1.219 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 1 (2022): Jurnal Riset Kefarmasian Indonesia; 214-133 2655-8289 10.33759/jrki.v4i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/219/140 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/222 2022-01-28T23:42:03Z jrki:ART driver

GAMBARAN INTERAKSI OBAT PENYAKIT JANTUNG KORONER DENGAN SINDROM METABOLIK PADA PASIEN RAWAT JALAN DI RS TK II DR. SOEPRAOEN MALANG Aprilianti, Rakhmadani Gadis Sekti, Beta Herilla Hidayati, Lilik Nur Drug Interaction Coronary Heart Disease Drug interaction is the effect of a drug that is caused when there are two or more drugs that interact and affect the body's response to treatment. The method used in this study is a descriptive study using a cross-sectional observational method with retrospective observations in October - December 2020. Patient data collection was obtained from patient medical records using a purposive sampling technique with inclusion criteria. A total of 89 patients were taken as samples. Data analysis using MEDSCAPE and drugs.com applications. A total of 82 prescriptions have the potential for drug interactions, where the most significant level of drug interaction is moderate level (81.48%, these include aspirin with candesartan and bisoprolol with amlodipine. The most drug interaction is the interaction between aspirin and bisoprolol which is classified as a minor interaction (17.74%). The most frequently used type of drug is bisoprolol (22.18%) and the most frequently used drug class is beta blocker APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-01-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/222 10.33759/jrki.v4i1.222 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 1 (2022): Jurnal Riset Kefarmasian Indonesia; 59-73 2655-8289 10.33759/jrki.v4i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/222/135 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/224 2022-10-01T04:35:04Z jrki:ART driver

OPTIMASI PENGGUNAAN HPMC DAN Na CMC PADA FORMULA TRANSDERMAL PATCH EKSTRAK ETANOL BUNGA TELANG (Clitoria ternatea L.) DENGAN METODE SIMPLEX LATTICE DESIGN Saryanti, Dwi Putri Setyadi, Ita Mustika Transdermal patch Clitoria ternatea L., Simplex Lattice Design HPMC, Na CMC Transdermal patch is drug delivery system that is pasted through the skin. These preparations can provide a constant drug release, easy to use, reduce the frequency of drug administration, eliminate first-pass metabolism, and reduce side effects such as gastric irritation and improve patient compliance. Blue pea (Clitoria ternatea L.) contains flavonoid compounds that have anti-inflammatory activity. This study aims to obtain the optimal comparison of HPMC and Na CMC as a polymer in the transdermal patch formula of the ethanol extract of the blue pea (Clitoria ternatea L.). Optimization was carried out using the Simplex Lattice Design method with Software Design Expert version 11. The responses used included pH tests, weight tests, thickness tests, folding tests and moisture content tests. The optimal formula obtained from the Simplex Lattice Design method was verified with the SPSS program using the one sample t-test method. The optimal formula of transdermal patch of blue pea ethanol extract was tested for acceptability to determine whether it was acceptable to the respondent or not. The optimal comparison of HPMC and Na CMC as a polymer with transdermal patch preparation of blue pea ethanol extract was 3.5%:1%, with a desirability value of 0.944. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-09-29 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/224 10.33759/jrki.v4i3.224 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 3 (2022): Jurnal Riset Kefarmasian Indonesia; 289-305 2655-8289 10.33759/jrki.v4i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/224/162 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/227 2022-01-28T23:42:03Z jrki:ART driver

TREN PENGGUNAAN ANTIBIOTIKA LINI 3 DI RS X BEKASI PERIODE TRIWULAN I TAHUN 2020 DIBANDINGKAN DENGAN TRIWULAN IV TAHUN 2019 Hasanah, Kurniatul PPRA Antibiotics Line 3 Antibiotics Quantitative Evaluation of Antibiotic Use Antibiotics are the most widely used drugs in the treatment of infections caused by bacteria. Resistance of microorganisms to antibiotics, pharmacokinetic and pharmacodynamic factors, drug interactions and side effects and cost factors are needed to be considered in their use. The use of antibiotics needs to be evaluated quantitatively and qualitatively. The study was conducted to determine and evaluate the use of line 3 antibiotics quantitatively in the X Bekasi Hospital in the first quarter of 2020 compared to the fourth quarter of 2019. It was descriptive study with retrospective data collection using total sampling technique. There are 13 types of antibiotics that are included in the line 3 antibiotics used at X Bekasi Hospital. The percentage of use of line 3 antibiotics in the first quarter of 2020 compared to the fourth quarter of 2019 increased by 26.9% for the use of amikacin 250 mg injection but decreased by 100% for the use of amikacin 500 mg injection, increased by 17.8% for the use of meropenem 0.5 g injection but decreased by 16.1% for the use of meropenem 1 g injection, decreased by 100% for the use of imipenem-cilastatin injection, linezolid 600 mg injection and vancomycin 500 mg injection, decreased by 212.5%, 53.6%, 41.2% and 69.2% each for the use of doripenem 500 mg injection, decreased, ceftazidime 1 g injection, cefepime 1 g injection and piperacillin tazobactam injection, and increased 75% for the use of tigecycline 50 mg injection. The use of line 3 antibiotics in X Bekasi Hospital was very large and varied in the fourth quarter of 2019 compared to the first quarter of 2020. A very significant amount was seen in the use of imipenem-cilastatin injection, linezolid 600 mg injection and vancomycin 500 mg injection. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-01-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/227 10.33759/jrki.v4i1.227 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 1 (2022): Jurnal Riset Kefarmasian Indonesia; 101-110 2655-8289 10.33759/jrki.v4i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/227/138 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/229 2022-02-02T04:39:41Z jrki:ART driver

UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN TABAT BARITO (Ficus deltoidea) TERHADAP BAKTERI Bacillus substillis DENGAN TINGKATAN POLARITAS PELARUT Rahayu, Sri Amaliah, Noor Patimah, Raudatul Bacillus substillis Antibacterial Tabat barito Tabat barito leaf (Ficus deltoidea) is a single leaf of a sole form, the leaf has round tip with a flat edge and a pointed base. These leaves have a smooth surface, coloured green above and brownish yellow beneath. This study aims to determine the antibacterial activity of polar, semi-polar and non-polar compounds contained in Tabat barito leaf extract extracted with solvents of different polarity. The highest bacterial inhibition was also measured against Bacillus substillis which is a gram-positive bacterial. The maceration method uses 3 levels of solvents with different polarities, started with a non-polar solvent (n-hexan), a semi-polar solvent (ethyl acetate) and finally macerated with a polar solvent (methanol). The bacterial activity test was done with  diffusion method. The results showed that the Tabat Barito leaf extract contained antibacterial compounds that were non-polar, semi-polar and polar. The highest inhibition of the hexane extract at concentration 15% with a clear zone diameter of 22.33 mm in very strong inhibition category against Bacillus substilis bacteria APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-01-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/229 10.33759/jrki.v4i1.229 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 1 (2022): Jurnal Riset Kefarmasian Indonesia; 34-45 2655-8289 10.33759/jrki.v4i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/229/133 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/230 2022-01-28T23:42:03Z jrki:ART driver

TINGKAT PEMAHAMAN TENAGA TEKNIS KEFARMASIAN TERHADAP OBAT PATEN DAN OBAT GENERIK DI KOTA PADANG Verawaty, Verawaty Dewi, Irene Puspa Kota, Fanny Millenia Patent Drugs Generic Medicines Pharmacy Technicians Understanding Patent drugs are drugs that still have patent rights and can only be produced by the manufacturer of the patent holder. while generic drugs are drugs whose patents have expired, so that they can be produced by all pharmaceutical companies. The purpose of this study was to determine the level of understanding of the pharmaceutical technical staff of Padang City on patent drugs and generic drugs. This research is a descriptive observational study using data collection instruments in the form of online questionnaires (google forms). The research variable is the respondent's level of understanding of generic and patent drugs. The respondents of this study were Pharmacy Technical Staff of Padang City, aged 20 years, both male and female, as many as 55 respondents. The sampling technique in this study was non-purposive sampling in accordance with the inclusion and exclusion criteria. Determination of the sample size in this study using the Slovin formula with an error rate of 5%. Collecting data by distributing online questionnaires via Google Forms. The data obtained is coded and entered into an Excel worksheet. The results showed that the level of understanding of the pharmaceutical technical staff of Padang City on patent drugs and generic drugs was categorized as sufficient (74.5%). APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-01-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/230 10.33759/jrki.v4i1.230 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 1 (2022): Jurnal Riset Kefarmasian Indonesia; 24-33 2655-8289 10.33759/jrki.v4i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/230/132 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/231 2022-01-28T23:42:03Z jrki:ART driver

POTENSI EKSTRAK N-HEKSAN, DIKLOROMETANA, ETIL ASETAT, DAN ETANOL 70% JAMUR DEWA (Agaricus blazei Murill) TERHADAP SEL MCF-7 Misgiati, Misgiati - MCF-7 cells Extraction levels God mushroom God mushroom is a functional food. It has pharmacological activity. This content has activity as an anticancer. The purpose of this study was to conduct a preliminary test to obtain an active ingredient capable of having anticancer activity on MCF-7 cells. The stages of the research are stratified extraction with several solvents. Extraction using maceration. The resulting extract was identified and tested for the anticancer activity of MCF-7 cells. The test uses the TLC method. The stationary phase with silica GF254, the mobile phase is n-hexane: ethyl acetate. Anticancer activity test using the MTT method. The results of the identification of each extract contained terpenoid secondary metabolites. Anticancer activity of MCF-7 cells with IC50 extract of n-hexane 15.0923 µg/ml, dichloromethane extract 17.4213 µg/ml, ethyl acetate extract 10.9132µg/ml with strong cytotoxicity criteria, while for ethanol extract IC50 675, 1236 µg/ml. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-01-27 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/231 10.33759/jrki.v4i1.231 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 1 (2022): Jurnal Riset Kefarmasian Indonesia; 11-23 2655-8289 10.33759/jrki.v4i1 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/231/131 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/237 2022-06-01T13:57:41Z jrki:ART driver

ANALISIS EFEKTIVITAS BIAYA METODE KB DAN KUALITAS HIDUP AKSEPTOR DI PUSKESMAS LOA JANAN Yanti, Wiwid Verri Warnida, Husnul Sentat, Triswanto Cost-Effectiveness Analysis IUD Injection contraceptive Oral contraceptive Loa Janan Health Center Family Planning (KB) is a national scale program to reduce birth rates and control population growth in Indonesia. Family planning has three phases. The first phase is the phase of delaying/preventing pregnancy. The second is the phase of spacing out pregnancies, and the third is the phase of terminating/terminating pregnancy/fertility. The use of contraceptives in family planning is an effort to prevent pregnancy. The most common contraceptive methods are the pill, injection, and IUD. The purpose of this study was to determine the cost-effectiveness of the use of oral contraceptive pills, contraceptive injections, and IUD at the Loa Janan Health Center. This study used a sample of 42 acceptors. The average cost of injection contraceptives is (Rp 25,000), pills (Rp 15,000), IUD (Rp 107,000) and the effectiveness of injection contraceptives (0.95%), pills (0.857%), and IUDs (0.867%). The ACER (Average cost-effectiveness ratio) value of injection contraceptives was Rp. 26,315, and 75% of the acceptors had an average quality of life. The ACER value of the pill was Rp. 17,502, and 85.7% of the acceptors had a good quality of life, the ACER value of the IUD was Rp. 123,414, and 60% of the acceptors had a good quality of life. The Pill-Injection's ICER (incremental cost-effectiveness ratio) value is Rp. 107,526. The ICER of IUD-Injection is Rp. -987,951, and the IUD-Pill (Rp.9,200,000). Hence, oral contraceptive gave a good quality of life and is more cost-effective than contraceptive injection and IUDs. Keywords: Cost-Effectiveness Analysis, IUD, injection contraceptive, oral contraceptive, Loa Janan Health Center APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-05-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/237 10.33759/jrki.v4i2.237 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 2 (2022): Jurnal Riset Kefarmasian Indonesia; 230-246 2655-8289 10.33759/jrki.v4i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/237/150 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/242 2025-05-20T07:26:43Z jrki:ART driver

OPTIMASI KOMBINASI COCOA BUTTER DAN MILK BUTTER SEBAGAI BASIS BODY BUTTER EKSTRAK ETANOL DAUN JAMBU BIJI (Psidium guajava Linn) Suradnyana, I Gede Made Mahardika, I Komang Gede Siada, Nyoman Budiartha Body Butter Cocoa Butter Factorial Desing Psidium guajava L. Guava leaf extract is known to contain flavonoids, a class of flavone compounds that have very strong antioxidant activity. The antioxidant activity of guava leaf ethanol extract as measured by the DPPH method showed an IC50 value of 72 µg/ml. Body butter preparations have a better ability to nourish and maintain skin moisture because they contain high oil components. Cocoa butter and milk butter are the bases that are widely used in body butter formulas and are able to maintain skin health. This study aims to determine the area of optimum composition of the combination of cocoa butter and milk butter in body butter preparations of guava leaf ethanol extract (Psidium guajava L.). This study used a factorial design with two factors, namely cocoa butter and milk butter and two levels, namely 2% and 4% for cocoa butter and 2% and 15% for milk butter. The observed responses were pH and spreadibility with data analysis using Design Expert and SPSS software. Based on the results of the research, the optimum area for the combination of cocoa butter and milk butter with the pH equation is Y = 6.00000 – 1.77504(X1) – 4.73345 (X2) + 1.8336(X1X2) and the dispersion equation is Y = 3 ,77692+0,366667(X1) – 0,005128(X2) + 0.033333(X1X2). The optimal composition area of cocoa butter and milk butter has been validated on the combination of 3% cocoa butter and 8,5% milk butter. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-05-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/242 10.33759/jrki.v4i2.242 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 2 (2022): Jurnal Riset Kefarmasian Indonesia; 195-214 2655-8289 10.33759/jrki.v4i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/242/148 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia http://creativecommons.org/licenses/by-nc-sa/4.0

oai:ojs.pkp.sfu.ca:article/243 2022-06-01T13:57:41Z jrki:ART driver

EVALUASI PENGGUNAAN ANTIBIOTIK DENGAN METODE GYSSENS PADA PASIEN PNEUMONIA DI RUMAH SAKIT BHAYANGKARA KUPANG PERIODE JULI – DESEMBER 2019 Yusuf, Muhammad Auliah, Nielma Sarambu, Hana Evangelista Pneumonia Gyssens method Antibiotics Pneumonia is a disease in Indonesia that has a high mortality rate in 2018. Pneumonia is an inflammation of the lungs caused by microorganisms (bacteria, viruses, fungi, parasites). Pneumonia caused by Mycobacterium tuberculosis is not included. While lung inflammation caused by non-microorganisms (chemicals, radiation, aspiration of toxic substances, drugs, etc.) is called pneumonitis. One of the treatment for pneumonia is antibiotics where the incidence of resistance in patients often occurs due to irrational use, therefore it needs to be monitored and evaluated by health workers. The purpose of this study was to determine the use of antibiotics in pneumonia patients at Bhayangkara Hospital Kupang with the Gyssens method according to the Minister of Health of the Republic of Indonesia No. 8 of 2015. The Gyssens method is an evaluation of the use of antibiotics to assess the accuracy of the use of antibiotics which includes the accuracy of indications, the accuracy of selection based on effectiveness, toxicity, price and spectrum, duration of administration, dose, interval, route and time of administration. The method used is non-experimental with a descriptive research design, the sample taken is 25 medical record data. The results of the research category 0 (precise and rational) were 84% or in other words the use of antibiotics was rational, category IVb (there were antibiotics that were less toxic) was 12% and in category IIb (inappropriate interval antibiotics) was 4%. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-05-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/243 10.33759/jrki.v4i2.243 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 2 (2022): Jurnal Riset Kefarmasian Indonesia; 215-229 2655-8289 10.33759/jrki.v4i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/243/149 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/246 2022-06-01T13:57:41Z jrki:ART driver

PENETAPAN KADAR AIR SIMPLISIA DAUN KEMANGI (Ocimum basilicum L.) BERDASARKAN PERBEDAAN METODE PENGERINGAN Wijaya, Andi Noviana, Noviana Drying method Moisture content Basil leaves Drying is one of the steps in making basil leaves simplicia. Drying is done to reduce the water content of simplicia. This study aims to determine the effect of the drying method on the water content of simplicia basil leaves. This research is an experimental post-test only group design. The basil leaves were dried using 2 methods, namely the direct sunlight method with a black cloth cover and the oven method at 50°C for 7 hours. The dried simplicia was then determined the water content using the gravimetric method. The water content data were analyzed using the Shapiro-Wilk test to determine the normality of the data, followed by the Independent T-test with a 95% confidence level. The results showed that the average moisture content of the drying method using the oven was 9,58±0.15% and the drying method using sunlight was 11,39±0.15%. These results indicate a significant difference (p≤0,05). This study concludes that different drying methods can affect the water content of basil leaves simplicia APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-05-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/246 10.33759/jrki.v4i2.246 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 2 (2022): Jurnal Riset Kefarmasian Indonesia; 185-194 2655-8289 10.33759/jrki.v4i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/246/147 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/250 2022-06-01T13:57:41Z jrki:ART driver

Daya Hambat Hand Sanitizer di Masyarakat: Apakah Efektif ? Taslim, Tuty Salim, Reny Dewi, Irene Puspa Hand Sanitizer Microbial Inhibition Effectiveness Hand sanitizer is one of the Household Health Supplies (PKRT) which is one of the human needs when the Covid-19 pandemic appears throughout the world. Panic at the beginning of the spread of Covid-19 has caused many people to buy and store hand sanitizers, resulting in shortages everywhere. WHO announced the composition for the manufacture of hand sanitizers. And the government allows making hand sanitizers without going through actual regulations so that hand sanitizers appear in several dosage forms such as sprays and gels suitable for antiseptic purposes. The inhibition of hand sanitizers against microbes needs to be tested considering its function as a microbial exterminator on human hands, so this research needs to be done to determine the effectiveness of hand sanitizers circulating in the community. The microbes used are Staphylococcus aureus and Escherichia coli. The sampling technique was carried out by purposive sampling and its effectiveness by using the disc diffusion method. The results obtained are that all hand sanitizers sampled have a diameter of inhibition as a strong antiseptic 10%, 50% sufficient and 40% weak. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-05-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/250 10.33759/jrki.v4i2.250 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 2 (2022): Jurnal Riset Kefarmasian Indonesia; 174-184 2655-8289 10.33759/jrki.v4i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/250/146 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/259 2022-06-01T13:57:41Z jrki:ART driver

PENGARUH PERBEDAAN METODE EKSTRAKSI DAUN JATI (Tectona grandis L.f) TERHADAP AKTIVITAS ANTIBAKTERI PADA Escherichia coli Sambodo, Dwi Kurniawati Marsel, Fransiska Sambodo, Herlina Prasetyowati Arlesia, Nandia Leaf of teak extract Extration Method Antibacterial The use of teak is limited to wood and stems with high economic value. The part of the teak that has not been utilized optimally is the teak leaf. Teak leaves are only used traditionally as food wrappers and traditional medicines. According to several studies, Sumthong (2007) in Setyawan (2012) stated that teak leaves contain several bioactive compounds, namely tektoquinone, tannic acid, gallic acid and several other organic acids. The presence of bioactive compounds in teak leaves can also be used as an antibacterial agent. This study was conducted to determine the effect of different extraction methods maceration, percolation and microwave Microwave Assisted Extraction on the antibacterial activity of teak leaves against Escherichia coli bacteria. From the research, it can be concluded that the different extraction methods of teak (Tectona grandis L.f) leaves have a significant effect on the antibacterial activity of Escherichia coli and the microwave extraction method is effective as an antibacterial against Escherichia coli as seen from the clear zone produced which is greater than the maceration and percolation extraction methods. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-05-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/259 10.33759/jrki.v4i2.259 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 2 (2022): Jurnal Riset Kefarmasian Indonesia; 156-173 2655-8289 10.33759/jrki.v4i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/259/145 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/260 2022-06-01T13:57:41Z jrki:ART driver

UJI AKTIVITAS ANTIBAKTERI EKSTRAK KULIT BATANG SEKILANG (Embelia borneensis Scheff) TERHADAP BAKTERI Escherichia coli DAN Staphylococcus aureus MENGGUNAKAN METODE DISC DIFFUSION Goetie, Inayah Herman Sundu, Reksi Supriningrum, Risa Antibacterial Embelia borneensis Escherichia coli Staphylococcus aureus Sekilang is one of the plants in North Kalimantan and is found in the Ampan Ibau Forest. This plant is empirically used by the people of Long Temuyat Village as a poison from natural ingredients to catch fish and as a leech repellent. The content of active compounds in sekilang bark extract include alkaloids, tannins, saponins, flavonoids. These compounds have the potential as antibacterial, so it is necessary to test the antibacterial activity. The purpose of this study was to determine the antibacterial activity of the sekilang bark extract against Escherichia coli and Staphylococcus aureus bacteria. The research phase included plant determination, sample collection, maceration extraction, and antibacterial activity test using the disc diffusion method with extract concentrations of 20%, 30%, and 40%. The results showed that the ethanol extract of the bark of sekilang has the potential to inhibit bacterial growth. The antibacterial activity of the bark extract of the cruciferous plant against Escherichia coli bacteria at concentrations of 20%, 30% and 40%, respectively, was 5.9 mm, 6.7 mm and 5.9 mm. Meanwhile, the activity of the bark extract against Staphylococcus aureus at concentrations of 20%, 30% and 40%, respectively, was 7.6 mm, 6.8 mm and 8.0 mm. The antibacterial activity of the bark extract against both bacteria was included in the moderate criteria. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-05-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/260 10.33759/jrki.v4i2.260 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 2 (2022): Jurnal Riset Kefarmasian Indonesia; 144-155 2655-8289 10.33759/jrki.v4i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/260/144 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/262 2022-06-01T13:57:41Z jrki:ART driver

GAMBARAN FUNGSI HATI PASIEN DIABETES MELITUS TIPE II DI SALAH SATU RUMAH SAKIT SWASTA DI KABUPATEN DEMAK PERIODE OKTOBER-DESEMBER 2020 Pangestuningsih, Megi Rukminingsih, Fef Liver Fungtion DM Type II Oral Antidiabetic Agent             Type II DM patients use Oral Antidiabetic Agent (OAA) continuously for a long time. OAA metabolism occurs in the liver. The use of OAA continuously in the long term can cause liver function disorders. The purpose of this study was to describe the liver function of type II DM patients who were treated with OAA in a private hospital in Demak District. This study is an observational descriptive study using retrospective data obtained from medical record documents of outpatients with type II DM for the period October – December 2020. Sampling using purposive sampling technique. The inclusion criteria were outpatients with type II DM, JKN participants who received OAA therapy for at least one year, aged 36 – 65 years old, have AST and ALT laboratory examinations. Patients who received combination therapy with insulin, had a history of impaired liver function were excluded. The results showed that from 62 patients there were 39 female patients (62.9%), the most patients aged 56-65 years were 32 patients (51.61%). The longest duration of use of OAA was 1 year, namely 29 patients (46.77%). The most widely used OAA was a combination of biguanides and sulfonylureas in 36 patients (58.07%). A total of 51 patients (82.25%) did not experience liver function damage and as many as 11 patients (17.75%) showed mild liver function damage with the duration of using OHO for more than 1 year and using OHO combination. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-05-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/262 10.33759/jrki.v4i2.262 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 2 (2022): Jurnal Riset Kefarmasian Indonesia; 134-143 2655-8289 10.33759/jrki.v4i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/262/143 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/264 2022-10-01T04:35:04Z jrki:ART driver

PERILAKU PENGGUNAAN ANTIBIOTIK TANPA RESEP DI APOTEK X DI KOTA PAYAKUMBUH SUMATERA BARAT Yulia, Mega Parsono, Ruddy Armal, Khairil Behavior of use Antibiotic Without prescription Antibiotic are organic compounds produced by various species of microorganisms and are toxic to other species of microorganisms. Irrational use of antibiotic can lead to resistance. The problem of resistance in addition to having an impact on morbidity and morality also has a very high economic and social impact. Research has been done on the behavior of using antibiotic without a prescription at pharmacy x in Payakumbuh City. The purpose of this study was to determine the use of antibiotic without a doctor's prescription at pharmacy X in Payakumbuh City. This research is non-experimental with data analyzed included the level of awareness of the use of antibiotic. The study used a descriptive method with random or accidental sampling with data collection using a questionnaire with 100 samples from 5296 populations. The results showed that the most widely used antibiotics were amoxicillin (46%); the type of disease that most patients treated with antibiotics was toothache (33%); the most sources of information about antibiotics came from friends or family (35%); the reason most people use antibiotics without a doctor's prescription is that previous treatment has a satisfactory effect (36%) and the level of patient awareness of the use of antibiotics is still in the sufficient category (42%). APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-09-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/264 10.33759/jrki.v4i3.264 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 3 (2022): Jurnal Riset Kefarmasian Indonesia; 397-413 2655-8289 10.33759/jrki.v4i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/264/171 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/268 2022-10-01T04:35:04Z jrki:ART driver

PENETAPAN KADAR ALKALOID TOTAL PADA EKSTRAK N-HEKSAN DAN ETANOL BIJI KETUMBAR (Coriandrum sativum) MENGGUNAKAN SPEKTROFOTOMETER UV-Vis setyaningrum, lindawati Susanti, Dhina Ayu Alkaloids Berberine Bromocresol green (BCG), Coriander (Coriandrum sativum) is one of the medicinal plants which is known to contain secondary metabolites such as flavonoids, tannins, terpenoids, saponins, steroids, and alkaloids. Alkaloids have therapeutic effects as antimalarials and cancer. Research in determining the alkaloids in coriander was carried out by separating the alkaloids from other substances using the soxhlet method extraction with two solvents ethanol and n-hexane. The total alkaloid content is determined using a UV-VIS spectrophotometer at wavelength 351,5 nm. The reaction of alkaloids with Bromocresol green (BCG) is obtained to form a yellow product. The use of berberine standard was obtained the total alkaloid content of ethanol and n-hexane extract in coriander seed (Coriandrum sativum) were 0.524% and 0.583% respectively, and the ratio of total alkaloid content of ethanol extract was smaller than that of n-hexane extract. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-09-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/268 10.33759/jrki.v4i3.268 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 3 (2022): Jurnal Riset Kefarmasian Indonesia; 353-365 2655-8289 10.33759/jrki.v4i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/268/166 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/269 2022-06-01T13:57:41Z jrki:ART driver

GAMBARAN PENGGUNAAN OBAT PADA PASIEN PENYAKIT GINJAL KRONIK (PGK) YANG MENJALANI HEMODIALISIS DI RS X BEKASI PERIODE JANUARI – MARET 2020 Prasetya, Niko Tanty, Herty Nur Iskandar, Honey Pranacistri, Retnayu Penyakit Ginjal Kronik (PGK) Hemodialisis Obat Ginjal Kronik Rumah Sakit X Bekasi Chronic Kidney Disease (CKD) is a condition of kidney damage that occurs for 3 months or more in the form of structural or functional abnormalities of the kidneys with or without a decrease in the Glomerular Filtration Rate. So far, treatment for CKD can be done by hemodialysis, Continuous Ambulatory Peritoneal Dialysis (CAPD) and kidney transplantation. This study aims to determine the description of the use of drugs in CKD patients undergoing hemodialysis at Hospital X Bekasi from January to March 2020. This study was conducted using a descriptive method. Sampling in January - March 2020 was carried out with the total sampling method, namely all electronic prescription sheets of CKD patients undergoing hemodialysis at Hospital X Bekasi. Data were collected by calculating the amount and percentage based on the active substance and class of drugs used by CKD patients undergoing hemodialysis. Based on the results of observations of electronic prescriptions of drugs used by CKD patients undergoing hemodialysis at Hospital X Bekasi during January - March 2020, it can be concluded that the use of drugs based on the active substance is Calcium carbonate 500 mg capsules as many as 10580 capsules (59.07%), Sodium bicarbonate 500 mg tablets 1725 tablets (9.63%), Gentamicin sulfate 80 mg/2 ml inj 868 ampoules (4.85%), Vitamin C (ascorbic acid) 200 mg/2 ml inj 753 ampoules (4.21% ), Recombinant human erythropoietin 3000 IU 678 injection (3.78%). APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-05-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/269 10.33759/jrki.v4i2.269 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 2 (2022): Jurnal Riset Kefarmasian Indonesia; 270-278 2655-8289 10.33759/jrki.v4i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/269/153 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/270 2022-06-01T13:57:41Z jrki:ART driver

GAMBARAN PENGETAHUAN MASYARAKAT TENTANG SWAMEDIKASI SAKIT GIGI DI RW 044 KELURAHAN BAHAGIA, BEKASI UTARA Iskandar, Honey Sukowati, Yudha Meryta, Aries Setyaningrum, Noor Affni Swamedikasi sakit gigi pengetahuan masyarakat The practice of self-medication is a lot of medication errors. Medication errors due to a lack of drug information. Self-medication is defined as the selection and use of medicines both herbal and synthetic drugs by a person to treat a disease or symptom that is self-recognized. In self-medication, it is best to follow the rational drug use requirements. The use of a drug is said to be irrational if the possibility of negative impacts received by the patient is greater than the benefits. The purpose of this study was to find out the description of knowledge about dental pain self-medication in RW 044 Bahagia, North Bekasi in April 2020, regarding the understanding of dental pain self-medication, the use of chemical drugs in dental pain self-medication, the use of traditional medicines in self-medication dental pain, where to get medicine for self-medication of dental pain, the reasons for self-medication of dental pain, and a source of drug information in self-medication for dental pain. The research method used is a descriptive research method to the community at RW 044 with the provision that 1 KK completes 1 questionnaire, with an age range of 25-64 years. The results of this study have a sufficient level of knowledge of 70 respondents (53.03%), So it can be concluded that the picture of community knowledge in RW 044 Bahagia, North Bekasi is sufficient. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-05-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/270 10.33759/jrki.v4i2.270 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 2 (2022): Jurnal Riset Kefarmasian Indonesia; 256-269 2655-8289 10.33759/jrki.v4i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/270/152 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/271 2022-06-01T13:57:41Z jrki:ART driver

GAMBARAN TINGKAT PERSEDIAAN OBAT ANTI HIPERTENSI DI APOTEK IMPHI PERIODE JANUARI – MARET 2020 Meryta, Aries Subagya, Guruh Prasetya, Niko Maulana, M Arman tingkat persediaan antihipertensi Apotek Imphi Hypertension or high blood pressure is the condition when blood pressure is at the value of 130/80 mmHg or more. This condition can be dangerous, if the patient's treatment is constrained by the quality management of a poor pharmaceutical installation (pharmacy). Efficient drug management is one of the most important factors in the success of overall management so that patients can obtain maximum treatment, and aim to avoid excess (stagnant) and deficiency (stockout) drug availability in pharmacies. The study aims to determine the degree of antihypertensive drug supply at Imphi Pharmacy from January to March 2020. This type of research uses non-experimental methods, which are types of research using quantitative descriptive methods. The sampling method uses a total sampling. The result is that all groups of antihypertensive drugs meet the average supply level of three months with a supply rate of ≥ 1.00 months, and there are two categories of drug stocks are ideal stock (supply levels ≥ 1.00 to ≤ 3.00) and stock is not ideal (inventory levels ≥ 3.00) and the most widely used antihypertensive drugs amlodipine 5 mg with an average use of 3 months as many as 1880 tablets with a stock rate of 1.22 months. All classes of antihypertensive drugs at Imphi Pharmacy each have a slowmoving drug resulting in a high level of drug supply. High levels of drug supply are influenced by several factors such as the number of declining drug requests, excess stock in the warehouse, and the transfer of the drug from generic to patent or otherwise by a physician. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-05-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/271 10.33759/jrki.v4i2.271 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 2 (2022): Jurnal Riset Kefarmasian Indonesia; 279-288 2655-8289 10.33759/jrki.v4i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/271/154 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/272 2022-06-01T13:57:41Z jrki:ART driver

EVALUASI MUTU FISIKA DAN KIMIA SEDIAAN KRIM LIP AND CHEEK DENGAN PEWARNA ALAMI EKSTRAK BUAH NAGA SUPER MERAH (Hylocereus Costaricensis) Efrilia, Mega Agustina, Ika Lestari, Tri Krim lip and cheek ekstrak buah naga super merah evaluasi mutu krim Lip and cheek adalah kosmetik dwifungsi yang dapat digunakan sebagai pewarna bibir sekaligus perona pipi. Berdasarkan hasil pengawasan BPOM diketahui banyak pewarna sintetis berbahaya yang disalahgunakan sebagai pewarna kosmetik. Buah naga super merah diketahui dapat digunakan sebagai pewarna alami karena memiliki kandungan zat warna antosianin. Antosianin adalah zat warna yang berperan memberikan warna merah berpotensi menjadi pewarna alami untuk pangan ataupun untuk kosmetik, sebagai pengganti pewarna sintetis yang lebih aman bagi kesehatan. Oleh karena itu, pada penelitian ini dilakukan evaluasi mutu fisik sediaan lip and cheek dengan pewarna alami ekstrak buah naga super merah. Sediaan dibuat menggunakan dua variasi formula, yaitu F0 dengan konsentrasi ekstrak 0% sebagai kontrol dan F30 dengan konsentrasi ekstrak 30%. Ekstrak buah naga super merah dibuat menggunakan metode maserasi daging buah naga selama tiga hari dengan pelarut etanol 96% yang kemudian dipekatkan dengan rotary evaporator hingga menjadi ekstrak kental. Daging buah naga dipilih karena kadar antosianin yang terkandung lebih tinggi dibandingkan antosianin yang terdapat pada kulit buah naga. Sediaan dibuat dengan mencampur Fasa I yang sudah mencair dengan Fasa II menggunakkan homogenizer. Krim Lip & Cheek secara organoleptik merupakan sediaan semi padat dengan warna merah muda, memiliki bau khas, dan homogen. Serta memiliki pH 5,01 dengan nilai viskositas 209.200 cps. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-05-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/272 10.33759/jrki.v4i2.272 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 2 (2022): Jurnal Riset Kefarmasian Indonesia; 247-255 2655-8289 10.33759/jrki.v4i2 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/272/151 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/281 2022-10-01T04:35:04Z jrki:ART driver

UJI RESISTENSI BAKTERI Escherichia coli DARI SUMBER AIR BAKU DI KARAWANG TERHADAP ANTIBIOTIK SIPROFLOKSASIN Diniarti, Fuji Ayu Kasasiah, Ahsanal Hilmi, Indah Laily Antibiotics Ciprofloxacin Escherichia coli Raw Water Infectious diseases are included in the ten most common diseases in Indonesia. The disease can be overcome by the use of antimicrobials, one of which is antibiotics. Antibiotics are drugs used to treat infections caused by bacteria. Excessive use of antibiotics without clear indications can have an impact on the occurrence of bacterial resistance to these antibiotics. One of the bacteria that is resistant to antibiotics is Escherichia coli. This study aims to determine the sensitivity of Escherichia coli isolated from raw water sources in Karawang to the antibiotic ciprofloxacin. Samples were obtained from irrigation water which is the source of raw water for one branch of Perumdam in Karawang. The samples were tested using Lactose Broth (LB) media, then confirmed using Eosin Methylene Blue (EMBA) media to confirm the presence of Escherichia coli bacteria equipped with Gram stain. Bacterial resistance test was carried out using Mueller Hinton Agar (MHA) media with disc diffusion method. The results showed that the average diameter of the clear zone formed around the paper disc was 30.16 mm. The isolates showed intermediate results against the antibiotic ciprofloxacin. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-09-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/281 10.33759/jrki.v4i3.281 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 3 (2022): Jurnal Riset Kefarmasian Indonesia; 414-429 2655-8289 10.33759/jrki.v4i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/281/172 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/283 2022-10-01T04:35:04Z jrki:ART driver

EVALUASI FORMULASI MASKER CLAY DARI EKSTRAK ETANOl DAUN PEPAYA (CARICA PAPAYA L.) SEBAGAI ANTI JERAWAT Fauziah, Fauziah Alvanny, Nurliza Andalia, Kiki Papaya Leaf Formulation Clay Mask Anti-acne Papaya Leaf Extract is known to contain alkaloid and flavonoid compounds that can inhibit the preparation of peptidoglycan in bacterial cells and reduce immunity in target organisms. For ease of use of papaya leaf extract, it is formulated in the form of a mask. This study aims to formulate a clay mask from papaya leaf ethanol extract and the effectiveness of anti-acne use of clay mask preparation of papaya leaf ethanol extract for 4 weeks. The method used in this study is an experimental method carried out at the AKAFARMA laboratory in Banda Aceh. The samples used were Formula 0, Formula 1, Formula 2 and Formula 3 masks of papaya leaf ethanol extract with concentrations for Formula 1 (2.5 %), Formula 2 (5%) and Formula 3 (7%). The results of the research on the physical properties and stability of the clay mask preparation on organoleptic testing showed that all formulas did not change color and odor for 4 weeks, but there was a change in shape at F0, FI, and FII on the 28th day. The homogeneity test of all preparations showed a homogeneous arrangement. The resulting pH test is 5.7-6.5, the resulting dispersion test is 5-5.5. The dried preparation test resulted in 25-30 minutes. and the anti-acne effectiveness test of each mask preparation F0, FI, FII, and FIII the average percentage reduction in the number of acne was 20.83%, 22.63%, 28.75%, and 50%. Papaya leaf ethanol extract clay mask FIII (7.5%) was the maximum in reducing the number of pimples on the volunteers' faces. The conclusion in this study is that papaya leaves can be formulated as a clay mask. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-09-29 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/283 10.33759/jrki.v4i3.283 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 3 (2022): Jurnal Riset Kefarmasian Indonesia; 306-320 2655-8289 10.33759/jrki.v4i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/283/163 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/290 2022-10-01T14:27:19Z jrki:ART driver

FORMULASI DAN EVALUASI FISIK MASKER GEL PEEL OFF DARI SERBUK SISIK IKAN MUJAIR (Oreochromis mossambicus) Mutmainnah, Mutmainnah Abdullah, Abulkhair Syawie, Muvida Fish Scales Tilapia Fish Peel Off Gel Mask Masker gel peel off merupakan salah satu kosmetik yang digunakan untuk perawatan kulit yang dapat memutihkan, mengecilkan pori-pori, melembabkan dan menutrisi kulit. Salah satu bahan yang dapat dijadikan bahan utama masker gel peel off adalah sisik ikan mujair (Oreochromis mossambicus). Sisik ikan mujair mengandung kolagen yang bermanfaat sebagai antiaging. Penelitian ini bertujuan untuk mendapatkan formula masker gel peel off dari sisik ikan yang terbaik dengan memvariasikan konsentrasi PVA (5% dan 10%) dan HPMC (2% dan 4%). Dalam penelitian ini dibuat 4 formula yang berbeda. Pada sediaan dilakukan pengujian karakteristik yang meliputi uji organoleptis, uji homogenitas, uji pH, uji daya sebar, uji waktu mengering, dan uji hedonik. Hasil penelitian menunjukkan sediaan yang dibuat sudah memenuhi kriteria. Semua formula memiliki tekstur semi padat, beraroma jeruk, dan berwarna abu-abu dan semua formula menunjukkan homogenitas yang baik. Hasil uji pH diperoleh: F1 (5,0), F2 (5,6), F3 (5,5), dan F4 (5,4). Hasil uji daya lekat diperoleh: F1 (400 g : 5,2 cm), F2 (600 g : 5,2 cm), F3 (600 g : 5,4 cm), dan F4 (600 g : 5,4 cm). hasil uji waktu mengering: F1 (55 menit), F2 (33 menit), F3 (33,3 menit), F4 (56,3 menit). Dapat disimpulkan bahwa serbuk sisik ikan mujair dapat dijadikan sediaan masker gel peel off. Formula 2 menjadi formula terbaik dengan konsentrasi PVA 10% dan HPMC 2%. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-09-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/290 10.33759/jrki.v4i3.290 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 3 (2022): Jurnal Riset Kefarmasian Indonesia; 321-331 2655-8289 10.33759/jrki.v4i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/290/167 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia

oai:ojs.pkp.sfu.ca:article/293 2022-10-04T11:45:49Z jrki:ART driver

FORMULASI LULUR BODY SCRUB BERAS KETAN HITAM (ORYZA SATIVA VAR. GLUTINOSA) DENGAN PERPADUAN YOGURT SEBAGAI ZAT AKTIF Agata, Shelly Dwi Jayadi, Lukky Body Scrub Black Glutinous Rice Yogurt Scrub is a cosmetic preparation for skin care that functions as an abrasive in the form of scurb granules that can remove dead skin cells from the epidermis. The scrub used in this study was derived from black glutinous rice (Oryza Sativa Var. Glutinosa) which contains antioxidant components and can help activate vitamin B1 which helps maintain healthy skin and helps skin look brighter. In addition, the components of the active substance are also needed. Yogurt was chosen as the active ingredient of the preparation because it has Alpha Hydroxy Acid (AHA) which can help the exfoliation process and help remove dead skin cells and increase the skin's natural moisture factor. The purpose of making body scrub preparations using yogurt as an active substance with varying concentrations of 0%, 5%, 10% and 15%. This research was conducted experimentally. The physical quality test of the preparation includes organoleptic test, homogeneity test, pH test, adhesion test, dispersibility test, stability test, and emulsion type test. The results show that the preparations made meet the physical evaluation of the scrub preparations meet the quality requirements, meet the organoleptic quality evaluation, namely the formulation of the scrub preparations F0, F1, F2, and F3 with semi-solid texture, purplish gray color with a mixture of black glutinous rice and yogurt. Each preparation is homogeneous. Emulsion type o/w. pH ranged from 7, 45 - 6, 74. It complies with the quality requirements of the spreadability test and has good emulsion stability. The conclusion of this study is that the F3 formulation with the addition of 15% yogurt has the best physical quality in the organoleptic test, homogeneity test, pH test, dispersibility test, stability test, and emulsion type test. APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) 2022-09-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article application/pdf http://jurnalfarmasi.or.id/index.php/jrki/article/view/293 10.33759/jrki.v4i3.293 Jurnal Riset Kefarmasian Indonesia; Vol. 4 No. 3 (2022): Jurnal Riset Kefarmasian Indonesia; 332-352 2655-8289 10.33759/jrki.v4i3 eng http://jurnalfarmasi.or.id/index.php/jrki/article/view/293/165 Copyright (c) 2022 Jurnal Riset Kefarmasian Indonesia 47a954198717a3503c51c6a0e2294526